Evidence map›Paper›PMID 39990337›Full record

ArticlebioRxiv : the preprint server for biology2025

Analysis of crosslinking sites suggests

Wei-Sheng Wu, Dong-En Lee, Chi-Jung Chung, Shang-Yi Lu, Jordan S Brown, Donglei Zhang, Heng-Chi Lee

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wei-Sheng WuDepartment of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Dong-En LeeDepartment of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Chi-Jung ChungDepartment of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Shang-Yi LuDepartment of Electrical Engineering, National Cheng Kung University, Tainan 701, Taiwan.
Jordan S BrownDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.
Donglei ZhangDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-2720-1414
Heng-Chi LeeDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-8154-906X

Funding

piRNA-mediated genome surveillance of germline transcriptsR01GM132457 · NIGMS · UNIVERSITY OF CHICAGO · PI LEE, HENG-CHI · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM132457
6 · The paper itself

Abstract

Small RNAs play critical roles in gene regulation in diverse processes across organisms. Crosslinking, ligation, and analyses of sequence hybrid (CLASH) experiments have shown PIWI and Argonaute proteins bind to diverse mRNA targets, raising questions about their functional relevance and the degree of flexibility in target recognition. As crosslinking-induced mutations (CIMs) provides nucleotide-resolution of RNA binding sites, we developed MUTACLASH to systematically analyze CIMs in piRNA and miRNA CLASH data in

Identifiers

PMID39990337
PMCPMC11844481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.