Evidence map›Paper›PMID 39990230›Full record

ArticleTheranostics2025

Renal tubular epithelial-derived follistatin-like 1 protects against UUO-induced renal fibrosis in mice via inhibiting NF-κB-mediated epithelial inflammation.

Zhuan Niu, Jiasen Guo, Xingzu Liu, Mo Chen, Yueyue Jin, Maolin Yao, Xiaoxu Li, Qianqian Che, Shuzi Li, Chenjie Zhang and 7 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Zhuan NiuCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Jiasen GuoCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Xingzu LiuCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Mo ChenCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Yueyue JinCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Maolin YaoCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Xiaoxu LiCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Qianqian CheCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Shuzi LiCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Chenjie ZhangCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Kunyue ShangguanCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Dekun WangDepartment of Pathology, School of Medicine, Nankai University, Tianjin 300071, China.
Chuan'ai ChenDepartment of Pathology, School of Medicine, Nankai University, Tianjin 300071, China.
Wenli YuDepartment of Anesthesiology, Tianjin First Central Hospital, Tianjin 300192, China.
Xiaoyue TanDepartment of Pathology, School of Medicine, Nankai University, Tianjin 300071, China.
Wen NingCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
Lian LiCollege of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

FibrosisFollistatin-Related ProteinsInflammationKidney TubulesNF-kappa BUreteral ObstructionAnimalsCell LineDisease Models, AnimalEpithelial CellsHumansKidneyMaleMiceMice, Inbred C57BLMice, KnockoutFollistatin-Related ProteinsFstl1 protein, mouseNF-kappa BFSTL1renal fibrosisrenal tubular epithelial inflammationUUO

Identifiers

PMID39990230
PMCPMC11840719

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.