Evidence map›Paper›PMID 39990211›Full record

ArticleTheranostics2025

Glucose homeostasis controls N-acetyltransferase 10-mediated ac4C modification of HK2 to drive gastric tumorigenesis.

Qiang Wang, Mengmeng Li, Chen Chen, Lei Xu, Yao Fu, Jiawen Xu, Chuanjun Shu, Bo Wang, Zhangding Wang, Changyu Chen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  14. Functional roles and mechanisms of NAT10-mediated RNA acFrontiers in cell and developmental biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qiang WangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Anhui Medical University; MOE Innovation Center for Basic Research in Tumor Immunotherapy; Anhui Province Key Laboratory of Tumor Immune Microenvironment and Immunotherapy, Hefei, China.
Mengmeng LiJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Chen ChenDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Anhui Medical University; MOE Innovation Center for Basic Research in Tumor Immunotherapy; Anhui Province Key Laboratory of Tumor Immune Microenvironment and Immunotherapy, Hefei, China.
Lei XuDepartment of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Yao FuDepartment of Pathology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Jiawen XuJiangsu Key Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China.
Chuanjun ShuDepartment of Bioinformatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China.
Bo WangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Anhui Medical University; MOE Innovation Center for Basic Research in Tumor Immunotherapy; Anhui Province Key Laboratory of Tumor Immune Microenvironment and Immunotherapy, Hefei, China.
Zhangding WangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Anhui Medical University; MOE Innovation Center for Basic Research in Tumor Immunotherapy; Anhui Province Key Laboratory of Tumor Immune Microenvironment and Immunotherapy, Hefei, China.
Changyu ChenDepartment of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
Tao SongDepartment of Gastrointestinal Surgery, Xuzhou Central Hospital, Xuzhou, China.
Shouyu WangDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Anhui Medical University; MOE Innovation Center for Basic Research in Tumor Immunotherapy; Anhui Province Key Laboratory of Tumor Immune Microenvironment and Immunotherapy, Hefei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarcinogenesisGlucoseHexokinaseN-Terminal Acetyltransferase EStomach NeoplasmsAnimalsAutophagyCell Line, TumorFemaleHomeostasisHumansMaleMiceMice, KnockoutN-Terminal AcetyltransferasesPrognosisGlucoseHexokinaseHK2 protein, humanNAT10 protein, humanN-Terminal Acetyltransferase EN-Terminal Acetyltransferasesac4Cgastric cancerglycolysisHK2NAT10

Identifiers

PMID39990211
PMCPMC11840738

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.