Evidence map›Paper›PMID 39989808›Full record

ArticleACS omega2025

Enhancing Implantable Medical Devices: Surface Functionalization of Titanium with Quaternary Ammonium Salts for Antibacterial Adhesion Properties.

Consuelo Celesti, Daniela Iannazzo, Elpida Piperopoulos, Bartolo Gabriele, Raffaella Mancuso, Giuseppa Visalli, Alessio Facciolà, Antonio Laganà

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Consuelo CelestiDepartment of Engineering, University of Messina, Messina, Contrada Di Dio I-98166, Italy.ORCID https://orcid.org/0000-0003-1393-477X
Daniela IannazzoDepartment of Engineering, University of Messina, Messina, Contrada Di Dio I-98166, Italy.ORCID https://orcid.org/0000-0003-2190-0035
Elpida PiperopoulosDepartment of Engineering, University of Messina, Messina, Contrada Di Dio I-98166, Italy.ORCID https://orcid.org/0000-0001-7960-4234
Bartolo GabrieleLaboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, Arcavacata di Rende (CS) 87036, Italy.ORCID https://orcid.org/0000-0003-4582-1489
Raffaella MancusoLaboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, Arcavacata di Rende (CS) 87036, Italy.ORCID https://orcid.org/0000-0001-7514-6096
Giuseppa VisalliDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina 98125, Italy.
Alessio FacciolàDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina 98125, Italy.
Antonio LaganàDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina 98125, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial colonization of titanium-based materials used in implantable medical devices represents a significant challenge in the dental and orthopedic fields, often leading to infections and implant failure. This study reports the surface modification of titanium discs with ammonium salts containing carbon atom chains of different lengths (from 6 to 12) to provide antibacterial properties to the modified metal surfaces while maintaining their biocompatibility. The chemically modified samples have been characterized by ATR-FTIR and SEM-EDX analyses and evaluated for roughness and hydrophilic behavior. This surface modification not only provides hydrophobic properties to titanium surfaces but also introduces a hindering environment for bacterial adhesion. Antibacterial tests performed against methicillin-sensitive and methicillin-resistant

Identifiers

PMID39989808
PMCPMC11840582

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.