Evidence map›Paper›PMID 39989782›Full record

ArticleACS omega2025

Crystallographic and Thermodynamic Evidence of Negative Coupling in the Flavin-Dependent Tryptophan Halogenases AbeH and BorH.

Md Ashaduzzaman, Kazi Lingkon, Aravinda J De Silva, John J Bellizzi

Abstract read
In one paragraph

Article in ACS omega, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Md AshaduzzamanDepartment of Chemistry and Biochemistry, The University of Toledo, Toledo, Ohio 43606, United States.
Kazi LingkonDepartment of Chemistry and Biochemistry, The University of Toledo, Toledo, Ohio 43606, United States.
Aravinda J De SilvaDepartment of Chemistry and Biochemistry, The University of Toledo, Toledo, Ohio 43606, United States.
John J BellizziDepartment of Chemistry and Biochemistry, The University of Toledo, Toledo, Ohio 43606, United States.ORCID https://orcid.org/0000-0003-4833-2795

Funding

Discovery and Characterization of Novel Halogenases from the Human Microbiome and from ArchaeaR15GM144877 · NIGMS · UNIVERSITY OF TOLEDO · PI BELLIZZI, JOHN J. · 2021 to 2025
$935k
NIGMS NIH HHS R15 GM144877
6 · The paper itself

Abstract

Flavin-dependent halogenases (FDHs) regioselectively halogenate aromatic substrates using halide ions, O

Identifiers

PMID39989782
PMCPMC11840605

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.