Evidence map›Paper›PMID 39989563›Full record

ArticleJournal of family medicine and primary care2025

Acanthosis nigricans and its association with cardio-metabolic risk factors in children with overweight/obesity: A school-based cross-sectional study.

Rashmi R Das, Manaswini Mangaraj, Saurav Nayak, Amit K Satapathy, Samarendra Mahapatro

Abstract read
In one paragraph

Article in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Rashmi R DasDepartment of Pediatrics, AIIMS, Bhubaneswar, Odisha, India.
Manaswini MangarajDepartment of Biochemistry, AIIMS, Bhubaneswar, Odisha, India.
Saurav NayakDepartment of Biochemistry, AIIMS, Bhubaneswar, Odisha, India.
Amit K SatapathyDepartment of Pediatrics, AIIMS, Bhubaneswar, Odisha, India.
Samarendra MahapatroDepartment of Pediatrics, AIIMS, Bhubaneswar, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acanthosis nigricans (AN) is a common finding often associated with hyperinsulinemia and childhood obesity. There has been a lack of studies evaluating the association of AN with underlying cardio-metabolic risk factors in children and adolescents. Our objective was to study the association between AN and cardio-metabolic risk factors in children with overweight/obesity. Methods: This cross-sectional study included school-going children (6-16 years of age) with overweight/obesity. Physical examination, anthropometry, and blood pressure (BP) data were collected. Fasting blood samples were collected to measure insulin, glucose, homeostasis model assessment index (HOMAIR), and lipid profile. Results: Of 1930 children screened, 545 had overweight/obesity, and were included. Boys to girls ratio was 1.27. AN was present in 46.4% of children. Children with AN had higher body mass index [BMI] ( Conclusions: Children with overweight/obesity who have AN have significant elevations of BP, insulin level, and HOMA-IR. AN is a clinical marker that seems to be associated with cardio-metabolic risk factors in children with overweight/obesity in the given study population.

Indexed as

Body mass indexHOMA-IRinsulin resistancemetabolic syndrome

Identifiers

PMID39989563
PMCPMC11844986

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