Evidence map›Paper›PMID 39989513›Full record

ReviewJournal of family medicine and primary care2025

The type of infections and the use of antibiotics among patients with rheumatoid arthritis: A review.

Asma D Alshammari, Mona Matar Aldhafeeri, Amal M Aldhafeeri, Maram Asaad Alanzi, Maha Bandar Almutairi, Jawaher Abdullah Alrasheedi, Thikra Adel Alsurur, Aeshah Dhahawi Alshammri

Abstract readReview
In one paragraph

Review in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Antibiotics for Rheumatologic Diseases: A Critical Review.International journal of molecular sciences · 2025
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asma D AlshammariIntensive Care Department, Maternity and Children Hospital, Hafar Albatin, Al-Qaysumah, Saudi Arabia.
Mona Matar AldhafeeriDepartment of Pharmacy, College of Pharmacy, University of Hafar Albatin, Hafar Albatin, Saudi Arabia.
Amal M AldhafeeriMedical Laboratories Department, College of Applied Medical Sciences, University of Hafar Albatin, Hafar Albatin, Saudi Arabia.
Maram Asaad AlanziMedical Laboratories Department, College of Applied Medical Sciences, University of Hafar Albatin, Hafar Albatin, Saudi Arabia.
Maha Bandar AlmutairiDepartment of Pharmacy, College of Pharmacy, University of Hafar Albatin, Hafar Albatin, Saudi Arabia.
Jawaher Abdullah AlrasheediDepartment of Pharmacy, College of Pharmacy, University of Hafar Albatin, Hafar Albatin, Saudi Arabia.
Thikra Adel AlsururDepartment of Pharmacy, College of Pharmacy, University of Hafar Albatin, Hafar Albatin, Saudi Arabia.
Aeshah Dhahawi AlshammriDepartment of Pharmacy, College of Pharmacy, University of Hafar Albatin, Hafar Albatin, Al-Qaysumah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients diagnosed with rheumatoid arthritis have a heightened susceptibility to infections, which may lead to higher rates of illness and death. The heightened susceptibility may arise from the illness itself, which causes changes in the body's innate cellular defense mechanisms, or from the medications used to manage the condition. The precise level of risk for infections associated with traditional disease-modifying anti-rheumatic drugs has not been fully elucidated. This review aimed To investigate the type of infections and the use of antibiotics among patients with rheumatoid arthritis. An electronic literature search was conducted using the MEDLINE database, with the indicated search keywords: infections, antibiotics, use, patients, rheumatoid, and arthritis. To identify relevant information, the search was limited to articles published between 2017 and 2024. The researchers used suitable search terms on Google Scholar to discover and examine relevant scholarly articles. The selection of articles was determined by several inclusion criteria. The research included publications that were published from 2017 to 2024. The study was organized into many sections, each including particular categories within the analysis section.we reportrd that : Within the developing age of focused synthetic treatments for RA, severe infections persist as the primary consequence of long-term treatment. In all patients with rheumatoid arthritis, it is necessary to conduct initial screenings for hepatitis B virus and tuberculosis. Additionally, it is important to administer vaccinations for specific pathogens (such as pneumococcal, herpes zoster, and influenza) before and during treatment. Aggressive therapy should be pursued to effectively manage disease activity in RA patients, while also maintaining constant vigilance for early signs of infections. Extra care should be given to senior rheumatoid arthritis (RA) patients who are over 65 years old and have other medical conditions. These people are often more susceptible to developing infections, regardless of the medication they get. The trials conducted with different antibiotics have confirmed the effectiveness of these medications in treating rheumatoid arthritis. Thus, it is plausible that the culprit responsible for rheumatoid arthritis is a microbe, namely periodontopathic bacteria.

Indexed as

Antibioticsarthritisinfectionspatientsrheumatoiduse

Identifiers

PMID39989513
PMCPMC11845013

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.