Evidence map›Paper›PMID 39989509›Full record

ArticleTobacco induced diseases2025

Exposure to secondhand smoke and physical disabilities in non-smokers: A national cross-sectional study with cotinine measurements from NHANES 2013-2018.

Jiahui He, Zhounan Wu, Yuhang Liang, Jinshen He

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Article in Tobacco induced diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jiahui HeDepartment of Orthopaedic Surgery, Third Xiangya Hospital of Central South University, Changsha, People's Republic of China.
Zhounan WuDepartment of Orthopaedic Surgery, Third Xiangya Hospital of Central South University, Changsha, People's Republic of China.
Yuhang LiangDepartment of Orthopaedic Surgery, Third Xiangya Hospital of Central South University, Changsha, People's Republic of China.
Jinshen HeDepartment of Orthopaedic Surgery, Third Xiangya Hospital of Central South University, Changsha, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSecondhand smoke (SHS) exposure is a significant health risk, but current research often overlooks its broader impact on functional impairments in the general public.

methodsThis study utilized serum cotinine levels (SCL) from the 2013-2018 NHANES dataset to investigate physical disabilities associated with SHS exposure. SCL represents the combined concentration of cotinine and hydroxycotinine. The physical disabilities assessed include difficulties with hearing, vision, concentration, walking, dressing or bathing independently, and running errands alone. Logistic regression was applied to evaluate the relationship between SCL and physical disabilities in adults, with stratified analyses by age, gender, and race. A p<0.05 was considered significant.

resultsLogistic regression analyses showed that SHS exposure was significantly associated with walking difficulty. Participants in the highest quartile of SCL (Q4) had significantly higher odds of walking difficulty compared to those in the lowest quartile (Q4 vs Q1, AOR=2.03; 95% CI: 1.24-3.31, p-trend=0.010). Higher hydroxycotinine were associated with increased walking difficulty (AOR=1.48; 95% CI: 1.06-2.08, p=0.030). Individuals in the highest quartile of hydroxycotinine (Q4) faced more difficulty running errands (AOR=2.09; 95% CI: 1.13-3.88, p-trend=0.036). Among males, the highest quartiles of cotinine and hydroxycotinine were more strongly associated with walking difficulty than in females (cotinine: AOR=2.92 vs 1.49; hydroxycotinine: AOR=3.23 vs 1.78). In adults aged ≥60 years, higher SCL, cotinine, and hydroxycotinine levels were significantly associated with walking difficulty (SCL, AOR=1.58; 95% CI: 1.24-2.02); cotinine, AOR=1.80; 95% CI: 1.21-2.67; hydroxycotinine, AOR=4.57; 95% CI: 1.92-10.89). An 'L'-shaped association was observed for ln(hydroxycotinine) and walking difficulty, with a significant association beyond -1.306 (AOR=2.57; 95% CI: 1.33-4.96, p=0.005).

conclusionsHigher SHS is significantly associated with various physical disabilities, especially in men and older adults.

Indexed as

cotininecross-sectionaldisabilityNHANESsecondhand smoke

Identifiers

PMID39989509
PMCPMC11843551

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.