Evidence map›Paper›PMID 39989448›Full record

ArticleDento maxillo facial radiology2025

Deep learning image enhancement for confident diagnosis of TMJ osteoarthritis in zero-TE MR imaging.

Chena Lee, Joonsung Lee, Sagar Mandava, Maggie Fung, Yoon Joo Choi, Kug Jin Jeon, Sang-Sun Han

Abstract read
In one paragraph

Article in Dento maxillo facial radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chena LeeDepartment of Oral and Maxillofacial Radiology, Yonsei University College of Dentistry, Seoul, 03722, Republic of Korea.ORCID 0000-0002-8943-4192
Joonsung LeeGE HealthCare, Seoul, 04637, Republic of Korea.
Sagar MandavaGE HealthCare, Atlanta, GA, 30188, United States.
Maggie FungGE HealthCare, New York, NY, 10032, United States.
Yoon Joo ChoiDepartment of Oral and Maxillofacial Radiology, Yonsei University College of Dentistry, Seoul, 03722, Republic of Korea.
Kug Jin JeonDepartment of Oral and Maxillofacial Radiology, Yonsei University College of Dentistry, Seoul, 03722, Republic of Korea.
Sang-Sun HanDepartment of Oral and Maxillofacial Radiology, Yonsei University College of Dentistry, Seoul, 03722, Republic of Korea.ORCID 0000-0003-1775-7862

Funding

Korean government NRF-2022R1A2B5B01002517National Research Foundation of Korea
6 · The paper itself

Abstract

objectivesThis study aimed to evaluate the effectiveness of deep learning method for denoising and artefact reduction (AR) in zero echo time MRI (ZTE-MRI). Also, clinical applicability was evaluated by comparing image diagnosis to the temporomandibular joint (TMJ) cone-beam CT (CBCT).

methodsCBCT and routine ZTE-MRI data were collected for 30 patients, along with an additional ZTE-MRI obtained with reduced scan time. Scan time-reduced image sets were processed into denoised and AR images based on a deep learning technique. The image quality of the routine sequence, denoised, and AR image sets was compared quantitatively using the signal-to-noise ratio (SNR) and qualitatively using a 3-point grading system (0: poor, 1: good, 2: excellent). The presence of osteoarthritis was assessed in each imaging protocol. Diagnostic accuracy of each protocol was compared against the CBCT results, which served as the reference standard. The SNR and the qualitative scores were compared using analysis of variance test and Kruskal-Wallis test, respectively. The diagnostic accuracy was assessed using Cohen's κ (<0.5 = poor; 0.5 to <0.75 = moderate; 0.75 to <0.9 = good; ≥0.9 = excellent).

resultsBoth the denoised and AR protocols resulted in significantly enhanced SNR compared to the routine protocol, with the AR protocol showing a higher SNR than the denoised one. The qualitative assessment also showed highest grade in AR protocol with statistical significance. The osteoarthritis diagnosis showed enhanced agreement with CBCT in denoised (κ = 0.928) and AR images (κ = 0.929) than routine images (κ = 0.707).

conclusionsA newly developed deep learning technique for both denoising and artefact reduction in ZTE-MRI presented clinical usefulness. Specifically, AR protocol showed significantly improved image quality and comparable diagnostic accuracy comparable to CBCT. It can be expected that this novel technique would help overcome the current limitation of ZTE-MRI for replacing CBCT in bone imaging of TMJ.

Indexed as

Deep LearningImage EnhancementMagnetic Resonance ImagingOsteoarthritisTemporomandibular Joint DisordersAdultArtifactsCone-Beam Computed TomographyFemaleHumansMaleMiddle AgedSignal-To-Noise Ratioconvolutional neural networkdigital radiographyMRItemporomandibular joint disorders

Identifiers

PMID39989448
PMCPMC12038245

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.