ArticleActa paediatrica (Oslo, Norway : 1992)2025
Severe Neonatal Morbidity Across Gestational Age: Monitoring Infants at High Risk of Mortality.
Article in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Long-Term Societal Costs After Births Before 24 Weeks of Gestation in Sweden.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Adverse Neonatal Outcomes Following Planned Vaginal Birth Compared to Planned Caesarean Birth: A Population-Based Study.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Ready for change? The effect of profession and organization on patient safety culture and organizational readiness for change - a cross-sectional study.BMC health services research · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
aimThis study aimed to quantify temporal trends in severe neonatal morbidity (SNM) and examine its association with neonatal mortality, stratified by gestational age.
methodsThis study included all live births in Sweden from 2007 to 2021. SNM types and subtypes were identified based on diagnoses and procedure codes for births ≥ 22 weeks' gestation, including complications within 27 days. Rates were calculated by gestational age, and temporal changes were assessed using rate ratios (RR) and 95% confidence intervals (CI). Adjusted relative risks (aRR) of neonatal death were also estimated.
resultsFrom 2007 to 2021, 47,048 (2.8%) cases of SNM were identified, rising from 2.2% in 2007 to 3.6% in 2021, mainly due to increased resuscitation/mechanical ventilation rates across all gestational ages. Infections rose among infants born at ≥ 37 weeks (0.59% in 2007-2011 to 0.77% in 2017-2021, RR 1.30, 95% CI, 1.24-1.37), but declined in those born at 22-31 weeks. Neurological morbidity, especially seizures, slightly increased in term and moderately preterm infants. Except for infants born at 22-27 weeks, neonatal mortality risks among infants with SNM were higher in infants with greater gestational ages.
conclusionDespite advances in neonatal care, SNM prevalence in Sweden increased from 2007 to 2021 across all gestational ages.
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