Evidence map›Paper›PMID 39989041›Full record

ArticleJournal of the National Cancer Institute. Monographs2025

Global perspectives on patient-centered outcomes: advancing patient-centered cancer clinical trials globally.

Cecilia Monge, Linsey Eldridge, Paul C Pearlman, Viji Venkatesh, Michelle Tregear, Patrick J Loehrer, Annette Galassi, Satish Gopal, Ophira Ginsburg

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute. Monographs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cecilia MongeCenter for Global Health, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.ORCID 0000-0002-5558-2744
Linsey EldridgeCenter for Global Health, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.
Paul C PearlmanCenter for Global Health, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.
Viji VenkateshThe Max Foundation, India and South Asia, Seattle, WA, United States.
Michelle TregearNational Breast Cancer Coalition, Washington, DC, United States.
Patrick J LoehrerCenter for Global Health, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.
Annette GalassiLeidos Biomedical Research, Inc, Frederick, MD, United States.
Satish GopalCenter for Global Health, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.
Ophira GinsburgCenter for Global Health, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.

Funding

ECOG-ACRIN NCORP Research Base - TMISTUG1CA189828 · NCI · ECOG-ACRIN MEDICAL RESEARCH FOUNDATION · PI Peter J ODwyer, MITCHELL D. SCHNALL · 2014 to 2026
$199.7M
NRG Oncology NCORP Research Base-BIQSFPUG1CA189867 · NCI · NRG ONCOLOGY FOUNDATION, INC. · PI Deborah Watkins Bruner, Lisa A. Kachnic · 2014 to 2026
$140.5M
Collaborations and NCORP Collective ManagementUG1CA189823 · NCI · MAYO CLINIC ROCHESTER · PI Evanthia Galanis, Olwen Hahn · 2014 to 2026
$120.6M
SWOG NCORP Research BaseUG1CA189974 · NCI · THE HOPE FOUNDATION · PI CHARLES D. BLANKE, DAWN HERSHMAN · 2014 to 2026
$80.6M
URCC NCORP Research BaseUG1CA189961 · NCI · UNIVERSITY OF ROCHESTER · PI Michelle C Janelsins, KAREN M. MUSTIAN · 2014 to 2026
$67.7M
Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiencyUG1CA189955 · NCI · PUBLIC HEALTH INSTITUTE · PI BRAD H POLLOCK, Michael E. Roth · 2014 to 2026
$62.5M
Wake Forest NCORP Research BaseUG1CA189824 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Emily Van Meter Dressler, GLENN J LESSER · 2014 to 2026
$57.9M
ACRIN UG1CA189828Children's Oncology Group 5UG1CA189955-11ECOGNCI Community Oncology Research Program UG1CA189867NCI NIH HHS UG1 CA189823NCI NIH HHS UG1 CA189824NCI NIH HHS UG1 CA189828NCI NIH HHS UG1 CA189867NCI NIH HHS UG1 CA189955NCI NIH HHS UG1 CA189961NCI NIH HHS UG1 CA189974SWOG UG1CA189974University of Rochester UG1CA189961Wake Forest University UG1CA189824
6 · The paper itself

Abstract

Patient-centered clinical trials prioritize the patient experience and outcomes that matter most to those affected by cancer. By centering on patient values and experiences, patient-centered outcomes research generates evidence to inform policies and practices, facilitating more personalized and effective cancer care. This manuscript explores the importance of patient-centered approaches in the global context, emphasizing challenges and opportunities for substantive patient engagement and the integration of patient-reported measures in clinical therapeutic trials in low- and middle-income countries. Despite important barriers such as limited infrastructure and funding constraints, leveraging innovative strategies and investing in research infrastructure and regulatory harmonization initiatives can enhance the capacity of low- and middle-income countries to conduct high-quality research and address the global burden of cancer more effectively. Through these efforts, patient-centered care and research can be extended to underserved populations, ensuring equitable access to cancer care worldwide.

Indexed as

Clinical Trials as TopicNeoplasmsPatient-Centered CareGlobal HealthHumansPatient Outcome AssessmentPatient ParticipationPatient Reported Outcome Measures

Identifiers

PMID39989041
PMCPMC11848040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.