Article in Glia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Caden M HenningfieldDepartment of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, California, USA.ORCID 0000-0002-9062-8672
Minh NgoDepartment of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, California, USA.ORCID 0009-0005-8830-4715
Kaitlin M MurrayDepartment of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, California, USA.ORCID 0000-0002-0185-2913
Nellie E KwangDepartment of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, California, USA.ORCID 0000-0001-8890-4976
Kate I TsourmasDepartment of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, California, USA.ORCID 0000-0001-8588-501X
Jonathan NeumannTransgenic Mouse Facility, University Laboratory Animal Services, Office of Research, University of California, Irvine, California, USA.
Zachary A PashkutzTransgenic Mouse Facility, University Laboratory Animal Services, Office of Research, University of California, Irvine, California, USA.
Shimako KawauchiTransgenic Mouse Facility, University Laboratory Animal Services, Office of Research, University of California, Irvine, California, USA.
Vivek SwarupDepartment of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, California, USA.
Thomas E LaneDepartment of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, California, USA.ORCID 0000-0003-0392-0825
Grant R MacGregorTransgenic Mouse Facility, University Laboratory Animal Services, Office of Research, University of California, Irvine, California, USA.
Kim N GreenDepartment of Neurobiology and Behavior, Charlie Dunlop School of Biological Sciences, University of California, Irvine, California, USA.ORCID 0000-0002-6049-6744
Funding
UC Irvine MODEL-ADU54AG054349 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Craig E Stark · 2017 to 2026
$71.9M
Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Origins, properties, and therapeutic potential of cells that repopulate the microglia-depleted adult brainR01NS083801 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Kim Green · 2014 to 2026
$5.6M
Defining mechanisms of disease and repair in a viral model of multiple sclerosisR35NS116835 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Thomas E Lane · 2020 to 2026
$5.0M
Training Program in Stem Cell Translational Medicine for Neurological DisordersT32NS082174 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI PETER John DONOVAN, Leslie Michels Thompson · 2013 to 2026
$3.3M
Microglia are necessary for cortical plaque formation in Alzheimer's diseaseRF1AG056768 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI GREEN, KIM · 2018 to 2018
$2.7M
Role of Disease-Associated Microglia in Alzheimer's diseaseR01AG081599 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Kim Green · 2024 to 2026
$2.3M
Neuroimmunology Training Program at the University of California, IrvineT32NS121727 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI Kim Green, Thomas E Lane · 2022 to 2026
$854k
Summer Medical student Aging and Alzheimer disease Research Training (SMAART) programT35AG076424 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Joshua Grill, Elizabeth Head · 2022 to 2026
$361k
Selective targeting and treatment of plaque associated microglia in a mouse model of Alzheimer’s DiseaseF31AG072852 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI HENNINGFIELD, CADEN MICHAEL · 2021 to 2023
The function of microglia during progression of Alzheimer's disease (AD) can be investigated using mouse models that enable genetic manipulation of microglial subpopulations in a temporal manner. We developed mouse lines that express either Cre recombinase (Cre) for constitutive targeting, or destabilized-domain Cre recombinase (DD-Cre) for inducible targeting from the Cst7 locus (Cst7
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Generation of an Inducible Destabilized-Domain Cre Mouse Line to Target Disease Associated Microglia. · full record | OpenQuestion