Evidence map›Paper›PMID 39988695›Full record

ArticleBMC infectious diseases2025

A cross-sectional study evaluating the screening, diagnosis and management of advanced HIV disease at the AIDS support organization service centre in Mbarara City, Southwestern Uganda.

Paddy Mutungi Tukamuhebwa, Isla Gemmell

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paddy Mutungi TukamuhebwaSchool of Health Sciences, Division of Population Health, Health Services Research and Primary Care, The University of Manchester, Oxford road, Manchester, UK. paddytmjwm@gmail.com.
Isla GemmellSchool of Health Sciences, Division of Population Health, Health Services Research and Primary Care, The University of Manchester, Oxford road, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionUganda has made significant progress in expanding access to ART over the years, however, currently up to 50% of People Living with HIV still enroll into HIV care with Advanced HIV Disease (AHD). This study therefore seeks to evaluate the screening, diagnosis and treatment of AHD at a high volume not for profit health facility in an urban setting in Southwestern Uganda.

methodsA cross-sectional study utilizing secondary data from a high volume, nonprofit health facility in southwestern Uganda was conducted from April 2022 to August 2022. The analysis included patient records for 994 newly diagnosed individuals and 76 patients who were not virologically suppressed. A descriptive analysis of the data was conducted, and the two groups (newly diagnosed and non-suppressed) were compared using chi-square tests or Fisher's exact test for categorical data, as well as the Mann Whitney U test for numerical data.

resultsThe prevalence of AHD as defined by a CD4 + cell count below 200 cells/mm

conclusionThis study demonstrates that the prevalence of AHD remains high, and the implementation of the AHD intervention package remains sub-optimal. The Ministry of Health and partners need to strengthen implementation strategies to improve the screening, diagnosis, and management of AHD.

Indexed as

HIV InfectionsMass ScreeningAdultCD4 Lymphocyte CountCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceUgandaYoung AdultAdvanced HIV diseaseManagementPrevalence

Identifiers

PMID39988695
PMCPMC11849361

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.