Evidence map›Paper›PMID 39988685›Full record

ArticleBMC oral health2025

A novel cone beam-CT approach for quantifying maxillary changes following secondary alveolar bone grafting in unilateral cleft patients.

Basel Khalil, Tobias Regnstrand, Reinhilde Jacobs

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Basel KhalilSection of Oral Radiology, Department of Dental Medicine, Division of Oral Diagnostics and Rehabilitation, Karolinska Institute, Huddinge, Sweden. baselkhalil51@outlook.com.
Tobias RegnstrandSection of Oral Radiology, Department of Dental Medicine, Division of Oral Diagnostics and Rehabilitation, Karolinska Institute, Huddinge, Sweden.
Reinhilde JacobsSection of Oral Radiology, Department of Dental Medicine, Division of Oral Diagnostics and Rehabilitation, Karolinska Institute, Huddinge, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo quantify longitudinal bone changes in the maxilla after secondary alveolar bone grafting (SABG) in patients with unilateral cleft lip and/or cleft palate (CL/P), and to describe the maxillary dimensions before and after SABG in all orthogonal planes using a Cone Beam Computed Tomography (CBCT)-based methodology.

methodsEthical approval was obtained to retrospectively analyze CBCT scans of children treated for unilateral alveolar clefts. Inclusion criteria encompassed individuals who underwent SABG before the eruption of the cleft-side permanent lateral incisor or, if absent, the permanent ca-nine, and had both preoperative and postoperative CBCT scans. A total of seven measurements of maxillary dimensions in all orthogonal planes, as well as in panoramic reconstruction, were conducted in the CBCT images. The normality of the data was confirmed with the Shapiro-Wilk test. A paired t-test was applied to assess significant differences between the preoperative and postoperative measurements (p < 0.05). The impact of age, gender, and their interrelation was evaluated by two-way ANOVA (p < 0.05).

resultsA total of 47 patients, comprising 32 males and 15 females, were selected based on the specified criteria. Notably, we observed a significant increase in sagittal, vertical, and transverse dimensions between the preoperative scans and those taken one year postoperatively (p < 0.05), irrespective of the patients' ages and genders. When considering gender, data indicated that male patients exhibited wider transverse dimensions in both the preoperative and postoperative measurements.

conclusionsThis study introduced a CBCT-based method to quantitatively assess maxillary changes in unilateral CL/P patients after SABG. The approach demonstrated continuous dimensional changes in all orthogonal planes. In addition, it described the maxillae dimensions in all planes. Future research can utilize this method for precise measurement of maxillary alterations and dimensions.

Indexed as

Alveolar Bone GraftingCleft LipCleft PalateCone-Beam Computed TomographyMaxillaAdolescentAge FactorsChildFemaleHumansMaleRadiography, PanoramicRetrospective StudiesSex FactorsCleft lip and/Or palate (CL/P)Cone beam computed tomography (CBCT)Maxillary changesOrthogonal planesQuantitative assessmentSecondary alveolar bone grafting (SABG)

Identifiers

PMID39988685
PMCPMC11849287

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.