Evidence map›Paper›PMID 39988589›Full record

ArticleNature communications2025

Memorability of novel words correlates with anterior fusiform activity during reading.

Oscar Woolnough, Nitin Tandon

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Oscar WoolnoughVivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX, USA. oscar.woolnough@uth.tmc.edu.ORCID http://orcid.org/0000-0002-5878-6865
Nitin TandonVivian L. Smith Department of Neurosurgery, McGovern Medical School at UT Health Houston, Houston, TX, USA.ORCID http://orcid.org/0000-0002-2752-2365

Funding

The Neural Code and Dynamics of the Reading NetworkU01NS128921 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI NITIN TANDON · 2022 to 2026
$4.1M
NINDS NIH HHS U01 NS128921U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) U01NS128921
6 · The paper itself

Abstract

Our memory for the words we already know is best predicted by their associated meanings. However, the factors that influence whether we will remember a new word after we see it for the first time are unclear. We record memory performance for 2100 novel pseudowords across 1804 participants during a continuous recognition task. Participants show significant agreement across individuals for which novel words were memorable or forgettable, suggesting an intrinsic memorability for individual pseudowords. Pseudowords that are similar to low-frequency known words, with sparse orthographic neighbourhoods and rarely occurring letter pairs, are more memorable. Further, using intracranial recordings in 36 epilepsy patients we show a region in the anterior fusiform cortex that shows sensitivity to the memorability of these pseudowords. These results suggest that known words in our lexicon act as a scaffold for remembering novel word forms, with rare and unique known words providing the best support for novel word learning.

Indexed as

MemoryReadingTemporal LobeAdultEpilepsyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRecognition, PsychologyYoung Adult

Identifiers

PMID39988589
PMCPMC11847940

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.