Evidence map›Paper›PMID 39988586›Full record

ArticleNPJ digital medicine2025

Multimodal machine learning to predict surgical site infection with healthcare workload impact assessment.

Kenneth A McLean, Alessandro Sgrò, Leo R Brown, Louis F Buijs, Katie E Mountain, Catherine A Shaw, Thomas M Drake, Riinu Pius, Stephen R Knight, Cameron J Fairfield and 7 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Kenneth A McLeanDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK. k.a.mclean@ed.ac.uk.ORCID http://orcid.org/0000-0001-6482-9086
Alessandro SgròColorectal Unit, Western General Hospital, Edinburgh, EH4 2XU, UK.ORCID http://orcid.org/0000-0001-5151-8342
Leo R BrownDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.ORCID http://orcid.org/0000-0001-6181-7020
Louis F BuijsColorectal Unit, Western General Hospital, Edinburgh, EH4 2XU, UK.
Katie E MountainDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Catherine A ShawDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Thomas M DrakeDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Riinu PiusDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Stephen R KnightDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Cameron J FairfieldDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Richard J E SkipworthDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Sotirios A TsaftarisAI Hub for Causality in Healthcare AI with Real Data, University of Edinburgh, Edinburgh, EH9 3FG, UK.
Stephen J WigmoreDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Mark A PotterColorectal Unit, Western General Hospital, Edinburgh, EH4 2XU, UK.ORCID http://orcid.org/0000-0002-1417-7515
Matt-Mouley BouamraneCentre for Medical Informatics, Usher Institute, University of Edinburgh, 9 Little France Rd, Edinburgh, EH16 4UX, UK.
Ewen M HarrisonDepartment of Clinical Surgery, University of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA, UK. ewen.harrison@ed.ac.uk.ORCID http://orcid.org/0000-0002-5018-3066
TWIST Collaborators

Funding

RCUK | Medical Research Council (MRC) MRC/CIC8/81
6 · The paper itself

Abstract

Remote monitoring is essential for healthcare digital transformation, however, this poses greater burdens on healthcare providers to review and respond as the data collected expands. This study developed a multimodal neural network to automate assessments of patient-generated data from remote postoperative wound monitoring. Two interventional studies including adult gastrointestinal surgery patients collected wound images and patient-reported outcome measures (PROMs) for 30-days postoperatively. Neural networks for PROMs and images were combined to predict surgical site infection (SSI) diagnosis within 48 h. The multimodal neural network model to predict confirmed SSI within 48 h remained comparable to clinician triage (0.762 [0.690-0.835] vs 0.777 [0.721-0.832]), with an excellent performance on external validation. Simulated usage indicated an 80% reduction in staff time (51.5 to 9.1 h) without compromising diagnostic accuracy. This multimodal approach can effectively support remote monitoring, alleviating provider burden while ensuring high-quality postoperative care.

Identifiers

PMID39988586
PMCPMC11847912

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.