Evidence map›Paper›PMID 39987960›Full record

ArticleContemporary clinical trials2025

Design and methods of a multi-level intervention to improve adherence to childhood cancer survivorship care by partnering with primary care providers: The BRIDGES randomized controlled trial.

Wilhelmenia L Ross, Yaiomy Santiago-Rivera, Ming T Tan, Megan M Roy, Stacy Bryant, Burton E Appel, Jacqueline Casillas, Jenna Demedis, Andrew B Smitherman, Leora I Horwitz and 4 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05448560 (BRidging Information Divides and Gaps to Ensure Survivorship), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05448560 naactive not recruitingnot on this map

BRidging Information Divides and Gaps to Ensure Survivorship: the BRIDGES Randomized Controlled Trial of a Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship

TypeinterventionalSponsorGeorgetown UniversityRan2023 to 2026Enrolled240ConditionsChildhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, PracticeArmsMulti-level Intervention of shared model of survivorship care, Comparison Group
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Wilhelmenia L RossGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC, United States of America.
Yaiomy Santiago-RiveraGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC, United States of America.
Ming T TanDepartment of Biostatistics, Bioinformatics and Biomathematics, Georgetown University, Washington, DC, United States of America.
Megan M RoyGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC, United States of America.
Stacy BryantGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC, United States of America.
Burton E AppelJoseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Children's Cancer Institute, Hackensack, NJ, United States of America.
Jacqueline CasillasUniversity of California at Los Angeles, Los Angeles, CA, United States of America.
Jenna DemedisDivision of Hematology/Oncology/BMT, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, United States of America.
Andrew B SmithermanUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Leora I HorwitzNew York University Grossman School of Medicine, New York, NY, United States of America.
Alejandra Hurtado-de-MendozaGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC, United States of America.
Jason A MendozaFred Hutchinson Cancer Center, Seattle, WA, United States of America; Center for Child Health, Behavior and Development, Seattle Children's Research Institute, Seattle, WA, United States of America; University of Washington, Seattle, WA, United States of America.
Sheila J SantacroceUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.
Nina S Kadan-LottickGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC, United States of America. Electronic address: nina.kadanlottick@georgetown.edu.

Funding

BRidging Information Divides and Gaps to Ensure Survivorship: the BRIDGES Randomized Controlled Trial of a Multilevel Intervention to Improve Adherence to Childhood Cancer SurvivorshipR01CA261881 · NCI · GEORGETOWN UNIVERSITY · PI KADAN-LOTTICK, NINA S · 2021 to 2025
$3.2M
NCI NIH HHS R01 CA261881
6 · The paper itself

Abstract

backgroundDespite heightened risk of chronic health conditions, <20 % of childhood cancer survivors (CCS) receive guideline-recommended surveillance for late effects. Barriers include avoidance of reminders, lack of knowledge, and costs. The goal of the BRIDGES Study is to evaluate the effects of a multi-level, remote intervention on adherence to guideline-recommended surveillance among CCS by partnering with primary care providers (PCPs).

methodsThis ongoing study is a multi-site, two-arm, prospective, parallel design, 1:1 randomized controlled non-inferiority trial (N = 240; n = 120/group). Eligibility criteria are: cancer diagnosis at age < 21 years, 2.0-4.0 years post-cancer therapy, and no previous specialty survivorship clinic care. The intervention includes: 1) patient survivorship education via telehealth with a cancer center nurse, including discussion of patient's individualized survivorship care plan (SCP), 2) ongoing patient-tailored health education within the electronic health record's patient portal, 3) a structured interactive phone call between the cancer center nurse and PCP, including discussion of patient's SCP, and 4) an in-person PCP visit for survivorship care. Patients randomized to the comparison group are contacted to schedule an in-person visit at their cancer center-based survivorship clinic. Adherence to guideline-recommended surveillance tests (primary outcome) is assessed at 1-year post-randomization (primary follow-up time point) and 2-years post-randomization (for durability). Patient knowledge, self-efficacy, and activation; PCP knowledge and self-efficacy; and process outcomes are also assessed.

conclusionModels of survivorship care that overcome existing barriers are needed. If efficacious, this scalable, remote intervention would be a valuable strategy to address barriers and bridge gaps in care to reach more CCS. CLINICAL

trial registrationClinicalTrials.gov Identifier: NCT05448560.

Indexed as

Cancer SurvivorsGuideline AdherenceNeoplasmsPrimary Health CareSurvivorshipAdolescentChildChild, PreschoolEquivalence Trials as TopicFemaleHumansMaleMulticenter Studies as TopicPatient Education as TopicProspective StudiesTelemedicinePatient compliancePatient handoffPrimary careRandomized controlled trialSurvivorship careSurvivors of childhood cancerTelehealth

Identifiers

PMID39987960
PMCPMC13042255

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.