Evidence map›Paper›PMID 39987935›Full record

ArticlePediatric dermatology

Pediatric Ewing's Sarcoma and Permanent Chemotherapy-Induced Alopecia: A Case-Control Study.

Madeline Lillich, Stuart Gold, Diana McShane

Abstract read
In one paragraph

Article in Pediatric dermatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Madeline LillichSchool of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-5217-5393
Stuart GoldDepartment of Pediatrics, Division of Hematology/Oncology, University of North Carolina, Chapel Hill, North Carolina, USA.
Diana McShaneDepartment of Dermatology, University of North Carolina, Chapel Hill, North Carolina, USA.

Funding

North Carolina Translational and Clinical Sciences Institute (NC TraCS)UM1TR004406 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NICHOLAS J SHAHEEN · 2023 to 2026
$37.5M
National Center for Advancing Translational Sciences (NCATS)NCATS NIH HHS UM1 TR004406NIH HHS UM1TR004406
6 · The paper itself

Abstract

Permanent chemotherapy-induced alopecia (PCIA), defined as the persistence of hair loss for > 6 months following chemotherapy cessation, is a rare pediatric diagnosis. A retrospective chart review was conducted to characterize cases of PCIA not previously reported in pediatric Ewing's sarcoma (ES) patients after completion of therapeutic chemotherapy, comparing demographic factors, cumulative chemotherapy dosing, family history of hair loss, and treatment methodologies with a control group. Of 12 patients with an history of pediatric ES, three were diagnosed with PCIA. Our findings suggest that PCIA can occur after treatment for ES in the pediatric population and that treatments, including topical and oral minoxidil, can be beneficial but may not result in complete hair regrowth.

Indexed as

AlopeciaAntineoplastic AgentsBone NeoplasmsSarcoma, EwingAdolescentCase-Control StudiesChildChild, PreschoolFemaleHumansMaleMinoxidilRetrospective StudiesAntineoplastic AgentsMinoxidilalopeciachemotherapydrug toxicityEwing's sarcomasurvivors of childhood cancer

Identifiers

PMID39987935
PMCPMC12883190

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.