Evidence map›Paper›PMID 39987907›Full record

ArticleFolia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)2025

Screening Voice Disorders: Acoustic Voice Quality Index, Cepstral Peak Prominence, and Machine Learning.

Ahmed Yousef, Ahmed M Yousef, Adrián Castillo-Allendes, Mark L Berardi, Juliana Codino, Adam D Rubin, Eric J Hunter

Abstract readComparative Study
In one paragraph

Article in Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmed Yousef
Ahmed M YousefCenter for Laryngeal Surgery and Voice Rehabilitation, Massachusetts General Hospital, Boston, Massachusetts, USA.
Adrián Castillo-AllendesDepartment of Communication Sciences and Disorders, University of Iowa, Iowa City, Iowa, USA.
Mark L BerardiDepartment of Communication Sciences and Disorders, University of Iowa, Iowa City, Iowa, USA.
Juliana CodinoLakeshore Professional Voice Center, Lakeshore Ear, Nose and Throat Center, St. Clair Shores, Michigan, USA.
Adam D RubinLakeshore Professional Voice Center, Lakeshore Ear, Nose and Throat Center, St. Clair Shores, Michigan, USA.
Eric J HunterDepartment of Communication Sciences and Disorders, University of Iowa, Iowa City, Iowa, USA.

Funding

Protecting Teachers’ Voices: Investigating Risk Factors, Conducting Cost AnalysisR01DC012315 · NIDCD · UNIVERSITY OF UTAH · PI HUNTER, ERIC J · 2013 to 2025
$5.5M
NIDCD NIH HHS R01 DC012315
6 · The paper itself

Abstract

introductionThe Acoustic Voice Quality Index (AVQI) and Smoothed Cepstral Peak Prominence (CPPs) have been reported to effectively support the assessment of voice quality in persons seeking voice care across many languages. This study aimed to evaluate the diagnostic accuracy of these two measures in detecting voice disorders in American English speakers, comparing their performance to machine learning (ML) models.

methodsThis retrospective study included a cohort of 187 participants: 138 patients with clinically diagnosed voice disorders and 49 vocally healthy individuals. Each participant completed two voicing tasks: sustaining [a:] vowel and producing a running speech sample, which were then concatenated. These samples were analyzed using VOXplot software for AVQI-3 (version 03.01) and CPPs. Additionally, four ML models (random forest, k-nearest neighbors, support vector machine, and decision tree) were trained for comparison. The diagnostic accuracy of the two measures and models was assessed using various evaluation metrics, including receiver operating characteristic curve and Youden Index.

resultsA cutoff score of 1.54 for the AVQI-3 (with 55% sensitivity and 80% specificity) and 14.35 dB for CPPs (with 65% sensitivity and 78% specificity) were identified for detecting voice disorders. Compared to an average ML sensitivity of 89% and specificity of 55%, CPPs offered a better balance between sensitivity and specificity, outperforming AVQI-3 and nearly matching the average ML performance.

conclusionsML shows great potential for supporting voice disorder diagnostics, especially as models become more generalizable and easier to interpret. However, current tools like AVQI-3 and CPPs remain more practical and accessible for clinical use in evaluating voice quality than commonly implemented models. CPPs, in particular, offers distinct advantages for identifying voice disorders, making it a recommended and feasible choice for clinics with limited resources.

Indexed as

Machine LearningSpeech AcousticsVoice DisordersVoice QualityAdultAgedDecision TreesFemaleHumansMaleMiddle AgedRetrospective StudiesSpeech Production MeasurementSupport Vector MachineYoung AdultAcoustic Voice Quality IndexCepstral Peak ProminenceMachine learningSpeech acousticsVoice disorders

Identifiers

PMID39987907
PMCPMC12353333

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.