Evidence map›Paper›PMID 39987791›Full record

ArticleNeurobiology of aging2025

Brain activation in older adults during odor identification is related to ApoE, t-tau/Aβ

Abigail Albertazzi, Claire Murphy

Abstract read
In one paragraph

Article in Neurobiology of aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abigail AlbertazziSan Diego State University Department of Psychology, San Diego, CA 92182, USA. Electronic address: aalbertazzi@sdsu.edu.
Claire MurphyUniversity of California, San Diego Department of Psychiatry, La Jolla, CA 92093, USA. Electronic address: cmurphy@sdsu.edu.

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DOUGLAS R GALASKO · 2019 to 2026
$34.9M
Olfactory and Visual Dysfunction as Potential Predictors of Preclinical Alzheimer's DiseaseR01AG062006 · NIA · SAN DIEGO STATE UNIVERSITY · PI MURPHY, CLAIRE L · 2019 to 2023
$2.8M
NIA NIH HHS P30 AG062429NIA NIH HHS R01 AG062006
6 · The paper itself

Abstract

Despite altered odor identification preceding and predicting Alzheimer's disease (AD) cognitive decline, an inadequate understanding of how AD pathology affects odor memory functions limits its use as a preclinical biomarker. Multivariate linear regression was applied to whole-brain blood-oxygen-level-dependent (BOLD) activations during odor identification task (OID) responses in older adults without dementia (N = 36, 44.4 % ε4 carriers, M

Indexed as

AgingAlzheimer DiseaseAmyloid beta-PeptidesApolipoprotein E4Apolipoproteins EBrainHippocampusOdorantsOlfactory PerceptionPeptide Fragmentstau ProteinsAgedAged, 80 and overBiomarkersFemaleHumansAmyloid beta-Peptidesamyloid beta-protein (1-42)Apolipoprotein E4Apolipoproteins EBiomarkersPeptide Fragmentstau ProteinsBiomarkerfMRIGenetic riskOlfactionStructural MRI

Identifiers

PMID39987791
PMCPMC13345118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.