Evidence map›Paper›PMID 39987527›Full record

ArticleEcoHealth2025

Continent-Wide Distribution of CMTV-Like Ranavirus, from the Urals to the Atlantic Ocean.

Lada S Lisachova, Artem P Lisachov, Oleg A Ermakov, Anton O Svinin, Polina I Chernigova, Sergey M Lyapkov, Renat I Zamaletdinov, Alexey V Pavlov, Svetlana S Zaks, Alexandr I Fayzulin and 2 more

Abstract read
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In one paragraph

Article in EcoHealth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Co-Exposure with the Herbicide 2,4-D Does Not ExacerbateAnimals : an open access journal from MDPI · 2025
    Article
  3. Age Structure of Water Frogs of the GenusAnimals : an open access journal from MDPI · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lada S Lisachova *Institute of Molecular and Cellular Biology, Russian Academy of Sciences, Siberian Branch, Novosibirsk, 630090, Russia.
Artem P Lisachov *Animal Genomics and Bioresource Research Unit (AGB Research Unit), Faculty of Science, Kasetsart University, 50 Ngamwongwan, Chatuchak, Bangkok, 10900, Thailand.
Oleg A ErmakovDepartment of Zoology and Ecology, Penza State University, Penza, 440026, Russia.
Anton O SvininInstitute of Cytology, Russian Academy of Sciences, Saint Petersburg, 194064, Russia.
Polina I ChernigovaInstitute of Environmental and Agricultural Biology (X-BIO), University of Tyumen, Tyumen, 625003, Russia.
Sergey M LyapkovDepartment of Biological Evolution, Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Renat I ZamaletdinovDepartment of Environmental Engineering and Water Resources Management, Kazan (Volga Region) Federal University, Kazan, 420008, Russia.
Alexey V PavlovVolzhsko-Kamsky National Nature Biosphere Reserve, Tatarstan Republic, 422537, Russia.
Svetlana S ZaksDepartment of Zoology and Ecology, Penza State University, Penza, 440026, Russia.
Alexandr I FayzulinInstitute of Ecology of Volga River Basin, Samara Federal Research Center of Russian Academy of Sciences, Togliatti, 445003, Russia.
Vyacheslav A KorzikovFederal Hygienic and Epidemiological Center in Kaluga Region of Rospotrebnadzor, Kaluga, 248018, Russia.
Evgeniy Simonov *Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Leninsky Prospect 33, Moscow, 119071, Russia. ev.simonov@gmail.com.ORCID 0000-0003-0194-4487

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ranavirosis is an emerging infectious disease of amphibians, fish, and reptiles caused by large dsDNA viruses of the genus Ranavirus associated with morbidity and mass mortalities worldwide. They are considered to be one of the major drivers of the ongoing amphibian biodiversity crisis. In this study, we investigated the prevalence and genetic diversity of ranaviruses in native and invasive populations of water frogs (Pelophylax spp.) across Russia using the DNA sample collection established in 2006-2016. The collection included samples collected in the wild and samples from wild-caught water frogs that had been kept in laboratories for a period of time. Overall, 52 out of 590 (8.8%) of wild frogs from 18 out of 94 (19.1%) sampling sites tested positive, including samples from invasive populations. Among the captive frogs, 71 out of 263 (27.0%) were positive and they had a significantly higher relative viral load. We found six major capsid protein gene haplotypes from 22 positive samples, all belonging to the common midwife toad virus (CMTV-like) ranaviruses, at multiple sites within the basins of three of Europe's largest rivers (Volga, Dnieper, and Don). Combined with previously published data, this study provides evidence for a continent-wide distribution of CMTV-like ranaviruses in Europe and strengthens the hypothesis of their endemism on the continent. Our study also highlights that the water frogs are important hosts for ranaviruses and could potentially act as vectors for infection transmission.

Indexed as

DNA Virus InfectionsRanavirusRanidaeAnimalsAtlantic OceanGenetic VariationRussiaalien speciesEast Europeemerging diseaseIridoviridaemajor capsid proteinranidae

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.