Evidence map›Paper›PMID 39987293›Full record

ArticleArchives of dermatological research2025

Association between psoriasis and Life's Essential 8 among adults in the United States.

Jian-Chun Hao, Xing Zhou, Shao-Wei Cheng

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Article in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jian-Chun HaoDepartment of Dermatology, Chuiyangliu Hospital Affiliated with Tsinghua University, No. 2, South Chuiyangliu Street, Chaoyang District, Beijing, 100022, China.
Xing ZhouDepartment of Dermatology, Beijing No.6 Hospital, Beijing, 100007, China.
Shao-Wei ChengDepartment of Dermatology, Chuiyangliu Hospital Affiliated with Tsinghua University, No. 2, South Chuiyangliu Street, Chaoyang District, Beijing, 100022, China. chengshaoweicsw@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the association between psoriasis and Life's Essential 8 (LE8), which has demonstrated an inverse relationship with various chronic diseases, though its link to psoriasis remains unexplored. In this cross-sectional study, we analyzed data from the National Health and Nutrition Examination Survey (NHANES) conducted during 2005 to 2006 and 2009 to 2014 that included participants who were 20 years or older. The LE8 score was calculated based on the American Heart Association's recommendations and categorized into three levels: low (0-49), moderate (50-79), and high (80-100). Psoriasis was identified using self-reported questionnaires. Weighted multivariable logistic regression and restricted cubic splines were applied to evaluate the relationship between LE8 scores and psoriasis. The study included 12,744 participants with an average age of 46.2 years (95% CI: 45.53-46.87 years); 6,289 (50.96%) were female, and 374 (2.9%) reported having psoriasis. The weighted mean LE8 score was 68.50 (95% CI: 67.94-69.07). After complete adjustment, a linear negative association was observed between psoriasis and the LE8 score (OR per 1 SD increase: 0.86, 95% CI: 0.75-0.99). Among the subscales, the health factors score showed a linear relationship with psoriasis, while a nonlinear relationship was found between psoriasis and the health behaviors score. Additionally, BMI, an LE8 component, demonstrated a significant association with psoriasis (OR per 1 SD increase: 0.84, 95% CI: 0.72-0.98) in multivariable logistic regression models. Subgroup and sensitivity analyses confirmed the robustness of these findings. We identified a linear negative relationship between psoriasis and LE8, demonstrating that improving LE8 management could serve as a potential strategy for preventing and managing psoriasis.

Indexed as

PsoriasisAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysSelf ReportUnited StatesYoung AdultChronic inflammatory dermatosisHealthLife’s essential 8 (LE8)PreventionPsoriasis

Identifiers

PMID39987293

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.