Evidence map›Paper›PMID 39987214›Full record

ArticleMolecular autism2025

Altered interactive dynamics of gaze behavior during face-to-face interaction in autistic individuals: a dual eye-tracking study.

Daniel Tönsing, Bastian Schiller, Antonia Vehlen, Kathrin Nickel, Ludger Tebartz van Elst, Gregor Domes, Markus Heinrichs

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Article in Molecular autism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Daniel Tönsing *Department of Psychology, Laboratory for Biological Psychology, Clinical Psychology, and Psychotherapy, University of Freiburg, Freiburg, Germany. daniel.toensing@unibas.ch.
Bastian Schiller *Department of Psychology, Laboratory for Biological Psychology, Clinical Psychology, and Psychotherapy, University of Freiburg, Freiburg, Germany. bastianschiller@web.de.
Antonia VehlenDepartment of Biological and Clinical Psychology, University of Trier, Trier, Germany.
Kathrin NickelDepartment of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Ludger Tebartz van ElstDepartment of Psychiatry and Psychotherapy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Gregor DomesDepartment of Biological and Clinical Psychology, University of Trier, Trier, Germany.
Markus HeinrichsDepartment of Psychology, Laboratory for Biological Psychology, Clinical Psychology, and Psychotherapy, University of Freiburg, Freiburg, Germany. heinrichs@psychologie.uni-freiburg.de.

Funding

Deutsche Forschungsgemeinschaft DO1312/5-1Deutsche Forschungsgemeinschaft HE5310/5-1HORIZON EUROPE European Research Council 101076414
6 · The paper itself

Abstract

backgroundPrevious eye-tracking research on autistic individuals has mostly examined the gaze behavior of one individual in response to social stimuli presented on a computer screen, suggesting that there is atypical gaze behavior. However, it is unknown how these findings translate to the interactive dynamics of gaze behavior during "face-to-face" encounters between two individuals. Only by analyzing the gaze behaviour of both interaction partners is it possible to determine the frequency of actual eye-contact and who initiates or breaks such periods of mutual eye gaze. The knowledge gained from this analysis could contribute to theorizing about the psychological mechanisms (e.g., gaze avoidance vs. gaze indifference) underlying autism.

methodsThe present study applied a novel dual eye-tracking setup that allows the assessment and analysis of the interactive dynamics of gaze behavior regarding (i) mutual eye gaze (i.e., eye contact), (ii) initiations, and (iii) break-ups of eye contact. Participants (37 autistic individuals, 37 age- and IQ-matched neurotypical individuals) performed a semi-standardized social interaction (i.e., Fast Friends Procedure) with a confederate (trained to interact in a standardized manner).

resultsEye contact was reduced in interactions involving autistic individuals. Additional analyses revealed that this reduction was primarily due to the more frequent breaking of eye contact by these individuals. We also found considerable heterogeneity among autistic individuals, with atypical gaze behavior present in only about half of the sample. LIMITATIONS: Further research is required to determine whether the interactive dynamics of gaze behavior observed in this dual eye-tracking setup can be generalized to real-world situations. Future studies could also include arousal-related physiological measures.

conclusionsBy tracking the gaze behavior of two interacting individuals, this study reveals specific atypicalities in the interactive dynamics of gaze behavior in a subset of autistic individuals, potentially informing diagnostic and therapeutic decisions. More broadly, our study highlights the added value of dual eye-tracking in elucidating the interactive nature of social encounters in both neurodiverse and neurotypical individuals.

trial registrationThe study was registered as a clinical trial before starting data collection ( https://drks.de/search/en/trial/DRKS00018957 ; Registration Date: 12/17/2019).

Indexed as

Autistic DisorderEye-Tracking TechnologyFixation, OcularSocial InteractionAdolescentAdultFemaleHumansInterpersonal RelationsMaleYoung AdultAutism spectrumDual eye-trackingNaturalistic gaze behaviorSocial interaction

Identifiers

PMID39987214
PMCPMC11846317

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.