Evidence map›Paper›PMID 39987203›Full record

ArticleMalaria journal2025

Identifying malaria risks amongst forest going populations in Mondulkiri province and Kampong Speu province, Cambodia: a large cross-sectional survey.

Ingrid Chen, Dyna Doum, David J McIver, Vanney Keo, Pisey Vong, Sophak Pech, Vanny Meth, Sour Bun, Kimheng Pen, Sopagna Chea and 9 more

Abstract read
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Ingrid Chen *Malaria Elimination Initiative, Institute for Global Health Sciences, University of California, San Francisco, USA. ingrid.chen@ucsf.edu.
Dyna Doum *Health Forefront Organization, Phnom Penh, Cambodia.
David J McIverMalaria Elimination Initiative, Institute for Global Health Sciences, University of California, San Francisco, USA.
Vanney KeoHealth Forefront Organization, Phnom Penh, Cambodia.
Pisey VongHealth Forefront Organization, Phnom Penh, Cambodia.
Sophak PechHealth Forefront Organization, Phnom Penh, Cambodia.
Vanny MethHealth Forefront Organization, Phnom Penh, Cambodia.
Sour BunMondulkiri Provincial Health Department, Senmonorom, Mondulkiri, Cambodia.
Kimheng PenMondulkiri Provincial Health Department, Senmonorom, Mondulkiri, Cambodia.
Sopagna CheaKampong Speu Provincial Health Department, Chbar Mon, Kampong Speu, Cambodia.
Kanha LyKampong Speu Provincial Health Department, Chbar Mon, Kampong Speu, Cambodia.
Kry HokKampong Speu Provincial Health Department, Chbar Mon, Kampong Speu, Cambodia.
Siv SovannarothNational Center for Parasitology, Entomology and Malaria Control, Phnom Penh, Cambodia.
Jafit TingMalaria Elimination Initiative, Institute for Global Health Sciences, University of California, San Francisco, USA.
Diane D LovinUniversity of Notre Dame, Notre Dame, IN, USA.
Joanne M CunninghamUniversity of Notre Dame, Notre Dame, IN, USA.
Élodie A VajdaMalaria Elimination Initiative, Institute for Global Health Sciences, University of California, San Francisco, USA.
Allison Tatarsky *Malaria Elimination Initiative, Institute for Global Health Sciences, University of California, San Francisco, USA.
Neil F Lobo *University of Notre Dame, Notre Dame, IN, USA.

Funding

Spatial repellents to reduce the outdoor transmission of malariaK01AI156182 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHEN, INGRID TING-TING · 2021 to 2024
$599k
Amplicon deep sequencing (Amp-Seq) of malaria parasite genomes towards understanding forest transmission systemsR03AI158800 · NIAID · UNIVERSITY OF NOTRE DAME · PI LOBO, NEIL · 2021 to 2022
$173k
Innovative Vector Control Consortium A134328National Institute for Health, National Institute of Allergy and Infectious Diseases K01AI156182NIAID NIH HHS K01 AI156182NIAID NIH HHS R03 AI158800NIH HHS 5R03AI158800-02
6 · The paper itself

Abstract

backgroundCambodia strives to eliminate all species of human malaria by 2025, requiring that foci among forest-exposed populations in remote settings be addressed. This study explores malaria risks amongst forest-exposed groups in Mondulkiri and Kampong Speu Provinces, Cambodia as part of a multi-stage study on novel mosquito bite prevention tools (Project BITE).

methodsA serial cross-sectional survey explored the demographics, housing structure openness, mosquito bite prevention habits, and protection from malaria amongst three target groups: forest goers who work in the forest, forest dwellers who live in the forest, and forest rangers who patrol forested regions. Malaria prevalence data was collected at three time points using rapid diagnostic tests (RDTs) for febrile individuals and qPCR for all participants. Infection locations and travel patterns of Plasmodium falciparum-infected individuals were analysed for clustering and the potential movement of infections.

results2935 participants were enrolled between October 2022 and February 2023, consisting of 1093 (37%) forest goers and 1787 (61%) forest dwellers across both provinces, and 55 (5%) forest rangers in Mondulkiri province. Most worked outdoors as farmers, day labourers, and forest collectors, and reported going to the forest five to seven days a week. For housing, 29% and 39% of participants reported living in partially open primary and secondary structures, respectively. The main methods of mosquito bite protection used were insecticide-treated nets, wearing long sleeves, and burning mosquito coils, with limited protection during the daytime and outside at night. All febrile individuals had negative RDT test results. For qPCR, 24 P. falciparum infections (< 1%) were detected among forest goers and dwellers, clustered in Pu Trom and Pu Nhav villages in Mondulkiri Province, and Banteay Roka and Banteay Roka Kirisenchey (M) villages in Kampong Speu Province. Plasmodium vivax cases were detected (216 cases, 5%) across all enrolled villages. Only two infections were found in forest rangers.

conclusionMalaria elimination strategies for forest-exposed populations in Cambodia should focus on vector intervention strategies that offer protection during the day and outside at night, and drug-based strategies to clear subpatent infections, targeting forest goers and dwellers in villages where cases are detected.

Indexed as

ForestsMalariaMalaria, FalciparumAdolescentAdultAgedCambodiaChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleMiddle AgedPlasmodium falciparumAsymptomaticForest dwellerForest malariaMalariaMalaria eliminationMosquitoVector controlVulnerable population

Identifiers

PMID39987203
PMCPMC11847376

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.