Evidence map›Paper›PMID 39987136›Full record

ReviewJournal of nanobiotechnology2025

Copper-based metal-organic frameworks for antitumor application.

Yangwei Qian, Chenxi Wang, Ruru Xu, Jin Wang, Qinyue Chen, Zirui Zhu, Quan Hu, Qiying Shen, Jia-Wei Shen

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yangwei QianSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China.
Chenxi WangSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China.
Ruru XuSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China.
Jin WangSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China.
Qinyue ChenSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China.
Zirui ZhuSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China.
Quan HuSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China. huq0203@163.com.
Qiying ShenSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China. qyshen718@hotmail.com.
Jia-Wei ShenSchool of Pharmacy, Hangzhou Normal University, Hangzhou, 311121, People's Republic of China. shen.jiawei@hotmail.com.

Funding

Interdisciplinary Research Project of Hangzhou Normal University 2024JCXK02Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2024KY236National Natural Science Foundation of China 22378090
6 · The paper itself

Abstract

It is urgent to exploit multifunctional materials and combined approaches for efficient antitumor effects. Copper-based metal-organic frameworks (Cu-MOFs) have excellent performances in catalysis, biocompatibility, photothermal conversion, and regulate metabolism, which make them attract more and more attention in antitumor application. Therefore, in this review, representative ligands, synthetic methods, antitumor mechanism, and antitumor applications of Cu-MOFs were provided. Special emphasis is placed on the recent antitumor applications of Cu-MOFs in drug carriers, antitumor therapy, tumor imaging, and theranostic, which are summarized with examples. Finally, we presented the dilemma faced by Cu-MOFs and offered a new perspective for future antitumor application. Hopefully, this review may serve as a reference for further development and application of Cu-MOFs.

Indexed as

Antineoplastic AgentsCopperMetal-Organic FrameworksNeoplasmsAnimalsDrug CarriersHumansTheranostic NanomedicineAntineoplastic AgentsCopperDrug CarriersMetal-Organic FrameworksAntitumor applicationAntitumor therapyCu-MOFsDrug carrierTheranosticTumor imaging

Identifiers

PMID39987136
PMCPMC11847370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.