Evidence map›Paper›PMID 39987131›Full record

ArticleNature communications2025

Engineering nanozyme immunomodulator with magnetic targeting effect for cascade-enzyodynamic and ultrasound-reinforced metallo-immunotherapy in prostate carcinoma.

Yandong Wang, Haodong Li, Junyang Lin, Yutang Li, Keqin Zhang, Hui Li, Qiang Fu, Yanyan Jiang

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
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  5. Article
  6. Article
  7. Review
  8. Review
  9. Ultrasonic-activated LaFundamental research · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. External Stimuli-Activable Single-Atom Nanozymes for Bioapplications.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  14. Review
  15. Review
  16. Article
  17. Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yandong Wang *Key Laboratory for Liquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, P. R. China.
Haodong Li *Department of Urology, Shandong Provincial Hospital, Shandong University, Jinan, P. R. China.
Junyang LinDepartment of Urology, Shandong Provincial Hospital, Shandong First Medical University, Jinan, P. R. China.
Yutang LiKey Laboratory for Liquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, P. R. China.
Keqin ZhangDepartment of Urology, Shandong Provincial Hospital, Shandong First Medical University, Jinan, P. R. China.
Hui LiKey Laboratory for Liquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, P. R. China.
Qiang FuDepartment of Urology, Shandong Provincial Hospital, Shandong First Medical University, Jinan, P. R. China. qiangfu68@163.com.ORCID http://orcid.org/0000-0003-1916-1229
Yanyan JiangKey Laboratory for Liquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science and Engineering, Shandong University, Jinan, P. R. China. yanyan.jiang@sdu.edu.cn.ORCID http://orcid.org/0000-0002-7866-4689

Funding

National Natural Science Foundation of China (National Science Foundation of China) 52472284Taishan Scholar Foundation of Shandong Province tstp20230658
6 · The paper itself

Abstract

Conventional immunotherapy exhibits low response rates due to the immunosuppressive tumor microenvironment (TME). To overcome this limitation, this study introduces ZFPG nanoparticles (ZFPG NPs) with ZnFe

Indexed as

Immunologic FactorsImmunotherapyNanoparticlesProstatic NeoplasmsAnimalsCell Line, TumorFerroptosisGlucose OxidaseHumansMaleMiceTumor MicroenvironmentUltrasonic TherapyGlucose OxidaseImmunologic Factors

Identifiers

PMID39987131
PMCPMC11846840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.