Evidence map›Paper›PMID 39987075›Full record

ArticleBMC public health2025

Insights into salt perception and cognitive impairment among middle-aged and older adults: a scoping review.

Azira Sazali, Suzana Shahar, Hasnah Haron, Nor Fadilah Rajab, Fatin Hanani Mazri, Theng Choon Ooi, Nurul Fatin Malek Rivan

Abstract readScoping Review
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Azira SazaliCentre for Healthy Ageing and Wellness (H-Care), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Suzana ShaharCentre for Healthy Ageing and Wellness (H-Care), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Hasnah HaronCentre for Healthy Ageing and Wellness (H-Care), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Nor Fadilah RajabCentre for Healthy Ageing and Wellness (H-Care), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Fatin Hanani MazriCentre for Healthy Ageing and Wellness (H-Care), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia.
Theng Choon OoiPremier Integrated Labs Sdn. Bhd, 55100, Kuala Lumpur, Malaysia.
Nurul Fatin Malek RivanCentre for Healthy Ageing and Wellness (H-Care), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, 50300, Kuala Lumpur, Malaysia. fatinmalek@ukm.edu.my.

Funding

Ministry of Higher Education, Malaysia FRGS/1/2023/SKK06/UKM/02/7
6 · The paper itself

Abstract

backgroundA decline in taste sensitivity from aging leads people with a higher salt threshold to frequently add more salt to their food, which attributed to decreased cognitive efficiency. This scoping review aimed to gather the latest evidence on the relationship between salt perception and cognitive impairment which is essential in the development of new intervention and prevention strategies.

methodsStudies published between January 2014 and March 2024 were searched across four databases: PubMed, the Cochrane Library, Scopus, and EBSCO. Data extraction involved gathering details on the study design, participant demographics, methods for assessing cognitive function and salt perception, considering confounding factors, and synthesizing the primary outcomes.

resultsSix studies were included in the analysis, five cross-sectional studies and a longitudinal study. These studies revealed various associations between salt perception and cognitive impairment. Specifically, findings from a three-year longitudinal study suggested that lower salt sensitivity was associated with poorer cognitive scores, which is consistent with the results of two other studies. However, the remaining three studies did not find significant differences (p > 0.05) in salt taste perception related to cognitive status. Furthermore, a study identified executive function as another significant factor influencing salt taste perception.

conclusionThese findings highlight the link between cognitive decline in salt perception, which provide an indication of salt intake and related health risks. There is a need to explore the mechanisms of salt taste sensitivity and its impact on cognitive health should be encouraged.

Indexed as

Cognitive DysfunctionSodium Chloride, DietaryTaste PerceptionAgedCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedSodium Chloride, DietaryCognitive impairmentExecutive functionMiddle-aged adultsOlder adultsSalt perceptionSalt sensitivity

Identifiers

PMID39987075
PMCPMC11846408

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.