ArticleBMC veterinary research2025
Prevalence and genetic characteristics of Campylobacter jejuni from laying-hens in Hubei Province, China.
Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- First Detection of Critical Carbapenemase Genes (NDM, OXA-48, VIM) in AvianAntibiotics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundCampylobacter jejuni (C. jejuni), a major global cause of foodborne bacterial diseases, accounts for more than 90% of all reported cases. Poultry is considered a major reservoir for the transmission of Campylobacter to humans. While extensive research has been conducted abroad on the occurrence and epidemiology of C. jejuni in laying hens, there are scant reports on its prevalence in layer chickens in China. The present study was designed to isolate C. jejuni from 482 cloacal swabs collected from seven laying hen farms located in Hubei Province between January and March 2024. Furthermore, the study aimed to explore the genetic diversity, antibiotic resistance, and virulence gene profiles of the isolated strains.
resultsThe overall prevalence of C. jejuni amounted to 4.36% (21/482). Whole-genome sequencing of these 21 isolates revealed 11 distinct sequence types (STs) and eight clonal complexes (CCs), with ST-6522 and CC-443 emerging as the predominant genotypes. Antimicrobial susceptibility testing against 11 antibiotics revealed high resistance rates among C. jejuni isolates, particularly towards ceftriaxone and enrofloxacin, where resistance was universal (100%). Similarly, high resistance levels were also observed for doxycycline (95.24%), ceftiofur (80.95%), tilmicosin (76.19%), and amoxicillin-clavulanic acid (57.14%). Through genomic resistance gene prediction, a total of eighteen resistance genes were identified within the 21 C. jejuni isolates. The most frequently occurring resistance genes were the gyrA (T86I) point mutation (95.14%), cmeR (95.14%), and tet(O) (95.14%). Notably, a robust correlation was discernibled between enrofloxacin resistance and the gyrA (T86I) point mutation, as well as between resistance to ceftriaxone and tilmicosin and the presence of the cmeR gene. Conversely, the correlations between other antibiotic resistance phenotypes and their corresponding resistance genes were less robust. A comprehensive analysis of virulence genes isolated from C. jejuni strains revealed a total of 117 virulence genes, categorized according to their functional roles. These categories encompass adhesion (cadF, jlpA, porA, pebA), invasion (ciaB), motility (flaA, flgB, flhB), toxin production (cdtA, cdtB, cdtC), and immune modulation (htrB, wlaN).
conclusionsOur results revealed the high resistance rate of C. jejuni from laying-hens in hubei Province, China, which will help the farms take the necessary action to develop effective mitigation strategies for reducing Campylobacter infection in poultry.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.