Evidence map›Paper›PMID 39987014›Full record

ArticleBMJ open2025

Estimating the indirect costs associated with adenocarcinoma or squamous cell carcinoma of the oesophagus in Switzerland: evidence from a cross-sectional survey.

Sandro T Stoffel, Arjun Bhadhuri, Paola Salari, Dieter Koeberle, Thibaud Koessler, Alexander Siebenhüner, Letizia Deantonio, Miklos Pless, Tim Kahl, Andreas Wicki and 2 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sandro T StoffelHealth Economics Facility, Department of Public Health, University of Basel, Basel, Switzerland sandro.stoffel@unibas.ch.ORCID http://orcid.org/0000-0002-0124-0941
Arjun BhadhuriInstitute of Pharmaceutical Medicine (ECPM), University of Basel, Basel, Switzerland.
Paola SalariInstitute of Pharmaceutical Medicine (ECPM), University of Basel, Basel, Switzerland.
Dieter KoeberleDepartment of Oncology, Sankt Claraspital AG, Basel, Switzerland.
Thibaud KoesslerHôpitaux Universitaires de Genève Service d'oncologie, Geneve, Switzerland.
Alexander SiebenhünerKlinik für Hämatologie und Onkologie, Hirslanden Hospital Hirslanden, Zurich, Switzerland.
Letizia DeantonioEnte Ospedaliero Cantonale, IOSI, Bellinzona, Switzerland.
Miklos PlessDepartment of Medical Oncology, Kantonsspital Winterthur, Winterthur, Switzerland.
Tim KahlKantonsspital Graubünden, Chur, Graubünden, Switzerland.
Andreas WickiUniversity of Zurich and University Hospital Zurich, Zurich, Switzerland.
César Oniangue-NdzaBristol-Myers Squibb Company, Steinhausen, Switzerland.
Matthias SchwenkglenksHealth Economics Facility, Department of Public Health, University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0001-7217-1173

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOur study investigated the impact of oesophageal cancer and its treatments on work productivity, leisure time, household chores and informal care in Switzerland. We assessed indirect costs for patients treated at different stages of adenocarcinoma or squamous cell carcinoma of the oesophagus. DESIGN AND

settingA retrospective, non-interventional survey was conducted among patients diagnosed with early or advanced oesophageal cancer in Switzerland. Between January 2023 and October 2023, 126 patients participated from seven clinical centres across German, French and Italian language regions. OUTCOME MEASURE: Self-reported lost time over a 4-week period, which was monetised to estimate indirect costs using respondents' approximate earnings derived from national statistics.

resultsOf the 126 patients, 24 (19.0%) were disease-free at the time of the study, while 15.1% of patients were in stage I, 13.5% in stage II, 27.0% in stage III and 25.4% in stage IV. Most patients, across age groups and disease stages, reported no impact on their leisure time (62.2%), household chores (70.3%) or informal care needs (78.4%) in the last 4 weeks. For those affected, the mean loss of time was 9.5 hours per week for leisure (n=28) and 13.3 hours for household chores (n=21). Additionally, patients received an average of 11.8 hours of informal care per week (n=16). Among the patients who were employed at the beginning of the 4-week recall period (n=25), 57.1% reduced the degree of employment and/or missed work due to the disease and its treatments during that time, while 46.7% experienced presentism (decreased productivity at work). The estimated mean indirect costs over a 4-week period was (Swiss Francs) CHF2005 (€1874) per patient, with loss of work productivity being the largest contributor.

conclusionOesophageal cancer in Switzerland affects patients' professional and personal lives, resulting in lost time and informal caregiving, leading to societal costs.

Indexed as

AdenocarcinomaCarcinoma, Squamous CellCost of IllnessEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansLeisure ActivitiesMaleMiddle AgedRetrospective StudiesSwitzerlandHEALTH ECONOMICSOesophageal diseaseSurveys and Questionnaires

Identifiers

PMID39987014
PMCPMC11848683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.