Observational studyBMJ open2025
Association between clinical and pulmonary function features and diagnosis of cough variant asthma: a case-control study.
Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06199830 (A Case-control Study on the Differentiation Between Cough Variant Asthma and Chronic Cough), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Case-control Study on the Differentiation Between Cough Variant Asthma and Chronic Cough
Who cites it
2 citing papers in PubMed.
- Prevalence of Overweight and Obesity and Their Impact on Lung Function in Healthy Bulgarian Children and Adolescents: A Cross-Sectional Study.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Article
- Female predominance in chronic cough: biological sex-related factors, mechanisms, and therapeutic targets-a narrative review.Frontiers in medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare physical information, such as age, sex, height, weight, body mass index (BMI) and pulmonary function test (PFT) results, between cough variant asthma (CVA) and chronic cough (CC) and establish a diagnostic model of CVA.
designA case-control study of patients with suspected CVA enrolled at The First Affiliated Hospital of Zhejiang Chinese Medical University.
settingOne leader unit of the National Key Specialised Pulmonary Disease Cooperation Group in China.
participantsEnrolled 545 patients who underwent PFT and bronchial provocation tests. OUTCOME MEASURES: We obtained physical information and pulmonary test data and established the model using logistic regression analysis. The Hosmer-Lemeshow goodness-of-fit test, area under the receiver operating characteristic curve (AUC), calibration plot and decision curve analysis were used to evaluate this model. All data were analysed using SPSS V.27 and RStudio software.
resultsThe CVA group had more female patients (%) (68.12% vs 51.48%, p value<0.001) and lower height (m) (1.61 (0.40) vs 1.65 (3.26), p value<0.001), weight (kg) (60 (56) vs 63 (85), p value<0.001) and BMI (kg/m
conclusionBMI, FVC% pred, FEV1/FVC (%) and MMEF% pred were used to establish the diagnostic model. Our model potentially indicates CVA. TRIAL REGISTRATION NUMBER: NCT06199830.
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Registered trials
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