Evidence map›Paper›PMID 39986388›Full record

SynthesisJournal of substance use and addiction treatment2025

A systematic review of smoking cessation interventions tested among Indigenous populations in the United States.

Samia Amin, Riana M Kawasaki, Thaddeus A Herzog, Sung-Shim Lani Park, Joseph Keawe'aimoku Kaholokula, Pallav Pokhrel

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of substance use and addiction treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samia AminPopulation Sciences Program, University of Hawai'i Cancer Center, University of Hawai'i at Manoa, 701 Ilalo St., Honolulu, HI 96813, United States of America. Electronic address: samin@cc.hawaii.edu.
Riana M KawasakiPopulation Sciences Program, University of Hawai'i Cancer Center, University of Hawai'i at Manoa, 701 Ilalo St., Honolulu, HI 96813, United States of America.
Thaddeus A HerzogPopulation Sciences Program, University of Hawai'i Cancer Center, University of Hawai'i at Manoa, 701 Ilalo St., Honolulu, HI 96813, United States of America.
Sung-Shim Lani ParkPopulation Sciences Program, University of Hawai'i Cancer Center, University of Hawai'i at Manoa, 701 Ilalo St., Honolulu, HI 96813, United States of America.
Joseph Keawe'aimoku KaholokulaPopulation Sciences Program, University of Hawai'i Cancer Center, University of Hawai'i at Manoa, 701 Ilalo St., Honolulu, HI 96813, United States of America; Department of Native Hawaiian Health, John A. Burns School of Medicine, University of Hawai'i at Manoa, 677 Ala Moana Boulevard, Suite 1016B, Honolulu, HI 96813, United States of America.
Pallav PokhrelPopulation Sciences Program, University of Hawai'i Cancer Center, University of Hawai'i at Manoa, 701 Ilalo St., Honolulu, HI 96813, United States of America.

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Pallav Pokhrel · 1996 to 2026
$56.2M
Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI SHIKUMA, CECILIA M. · 2021 to 2025
$15.5M
Cancer Research Education, Advancement, Training and Empowerment (CREATE) in the PacificR25CA244073 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Joseph Keawe'aimoku Kaholokula, LENORA WM LOO · 2020 to 2026
$1.9M
NCI NIH HHS P30 CA071789NCI NIH HHS R25 CA244073NIGMS NIH HHS U54 GM138062
6 · The paper itself

Abstract

introductionSmoking remains highly prevalent among Indigenous populations in the U.S., contributing to cardiovascular and cancer health disparities. Tailored smoking cessation interventions can reduce these disparities among Indigenous people, but the current evidence regarding the effectiveness of such extant interventions is unclear. This review aimed to collate evidence about the smoking cessation interventions tested among Indigenous groups in the U.S.

methodsThe study systematically searched PubMed, EMBASE, and Web of Science in September 2023 for experimental or quasi-experimental studies of smoking cessation interventions among Indigenous adults in the U.S. The Cochrane guidelines assessed study bias. Outcomes included self-reported and bio-verified smoking abstinence.

resultsThe review included eight studies, comprising 7 randomized control trials (RCTs) and 1 quasi-experimental trial evaluating multi-component interventions. The interventions included counseling, education, cultural tailoring, pharmacotherapy, mobile medical apps, and social media. The smoking abstinence outcomes varied. Four RCTs found no significant differences in self-reported or bio-verified abstinence between groups. Two RCTs showed significantly higher self-reported abstinence with culturally tailored interventions, while two postpartum RCTs found no difference between groups. The one-group quasi-experimental study showed a retention rate of 71 % and an abstinence rate of 31 % at 6-month follow-up. While results appear promising for tailored, multi-faceted approaches, abstinence differences between interventions and control groups overall remain inconsistent.

conclusionsThis review suggests that culturally tailored, technology-assisted smoking cessation interventions that strategically utilize pharmacotherapies may hold promise for U.S. Indigenous populations. However, the review emphasizes the need to test large-scale interventions that utilize more personalized strategies and community-based participatory approaches as well as the need for experimental trials that bio-verify abstinence.

Indexed as

Smoking CessationAmerican Indian or Alaska NativeCounselingHumansUnited StatesIndigenous populationInterventionQuit smokingSmoking abstinenceSmoking cessationUnited States

Identifiers

PMID39986388
PMCPMC12009202

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.