ReviewAnnals of intensive care2025
Thrombocytopenia in the intensive care unit: diagnosis and management.
Review in Annals of intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Determinants of thrombocytopenia in critically ill patients: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Redefining neonatal thrombocytopenia: an evidence-based approach, improved by the refineR algorithm.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Severe Thrombocytopenia in Actinotignum schaalii Bacteremia: A Case Report With Review of the Literature.Cureus · 2026Article
- Development and Validation of an Interpretable Machine Learning-Based Clinical Prediction Model for Short-Term Mortality in Intracerebral Hemorrhage With Thrombocytopenia: A Multicenter Study.CNS neuroscience & therapeutics · 2026Article
- Consumption-like Thrombocytopenia Phenotype Predicts ICU Mortality with Particular Relevance in Patients with Malignancy: A Retrospective Single-Center Cohort Study of 2188 Patients.Journal of clinical medicine · 2026Article
- ITP, easy as EBV: a rare case of severe immune thrombocytopenic purpura secondary to Epstein-Barr virus.Blood science (Baltimore, Md.) · 2026Article
- Prognostic impact of platelet count trajectories in acute decompensated heart failure: a retrospective cohort analysis.BMC cardiovascular disorders · 2026Article
- Prognostic Value of International Normalized Ratio and Thrombocytopenia in Early Risk Stratification of Septic Patients.Biomedicines · 2026Article
- Safety recommendations on laboratory and blood count values for early mobilization in critically ill adults: an expert consensus.Critical care science · 2026Article
- Revisiting the Concept of DIC: A Phenotype-guided Framework for Modern Hemostatic Medicine.Juntendo medical journal · 2026Review
- Aspartate Aminotransferase-to-Platelet Ratio Index (APRI) as a Predictor of Mortality in Patients with Femoral Fracture: A Retrospective Cohort Analysis.Therapeutics and clinical risk management · 2026Article
- Clinical characteristics of pyogenic liver abscess patients with multiple organ dysfunction syndrome and development and validation of a predictive model.Frontiers in cellular and infection microbiology · 2026Article
- Dynamic platelet profiles in the emergency department and their predictive value for 28-day all-cause mortality in septic patients.PloS one · 2026Article
- Coefficient of variation of platelet count as a prognostic Indicator for intracerebral hemorrhage: findings from a multicenter cohort.Frontiers in neurology · 2026Article
- Prevalence, Risk Factors, Characteristics, and Clinical Outcomes of Thrombocytopenia in the Intensive Care Unit: A Prospective Single-Center Cohort Study.Critical care research and practice · 2026Article
- Stratified assessment of platelets in sepsis: from dynamic counts to functional phenotypes.Frontiers in immunology · 2026Review
- Postoperative Thrombocytopenia in Cardiac Surgery: Patterns, Differential Diagnosis and Management of Heparin-Induced Thrombocytopenia (HIT).Journal of clinical medicine · 2025Review
- Platelet transfusion response in critically ill patients with thrombocytopenia: a retrospective study and predictive nomogram in a general ICU population.Annals of medicine · 2025Article
- The Complex Role of MAPK/ERK Signaling Pathway in Different Types of Thrombocytopenia.Current issues in molecular biology · 2025Review
- Safety and risk factors of PICC insertion in hematologic malignancy patients with thrombocytopenia: a retrospective study.Annals of hematology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis narrative review aims to describe the epidemiology and aetiologies of thrombocytopenia in critically ill patients, the bleeding risk assessment in thrombocytopenic patients, and provide an update on platelet transfusion indications.
resultsThrombocytopenia is a common disorder in critically ill patients. The classic definition relies on an absolute platelet count below 150 × 10
conclusionThrombocytopenia in critically ill patients is very frequent with various etiologies, and is associated with worsened prognosis, with or without bleeding complications. Interventional trials focused on critically ill patients are eagerly needed to better delineate the benefits and harms of platelet transfusions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.