Solid-Phase Pyrolysis Synthesis of Amino Acid-Based Nitrogen-Doped Carbon Dots as an "On-Off-On" Fluorescent Probe for the Detection of Copper Ions and Glutathione.

Zhuoru Yao, Cunjin Wang, Zixin Ma, Ruixin Huang, Baozhong Wang, Jing Zhang, Xiaoliang Zhao, Weijie Zhang, Huanxian Shi

Abstract read

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Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

9 authors.

Zhuoru Yao *School of Health Engineering, Lanzhou University of Information Science and Technology, Lanzhou, 730050, PR China.

Cunjin Wang *School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, 730050, PR China. wangcunjin@lut.edu.cn.

Zixin MaSchool of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, 730050, PR China.

Ruixin HuangSchool of Health Engineering, Lanzhou University of Information Science and Technology, Lanzhou, 730050, PR China.

Baozhong WangSchool of Health Engineering, Lanzhou University of Information Science and Technology, Lanzhou, 730050, PR China.

Jing ZhangSchool of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, 730050, PR China.

Xiaoliang ZhaoSchool of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, 730050, PR China.

Weijie ZhangSchool of Life Science and Engineering, Lanzhou University of Technology, Lanzhou, 730050, PR China.

Huanxian ShiSchool of Pharmacy, Shaanxi University of Chinese Medicine, Shaanxi University Engineering Research Center of Traditional Chinese Medicine and Aroma Industry, Xianyang, 712046, PR China. shihuanxian@sntcm.edu.cn.

Funding

Gansu Provincial Natural Science Fund 23JRRA840National Natural Science Foundation of China 82405028 and 32260231

6 · The paper itself

Abstract

This study introduces the synthesis of amino acid-based nitrogen-doped carbon dots (N-L-Ser-CDs) from L-serine (L-Ser) and urea through a straightforward and economical one-step solid-phase pyrolysis process. The incorporation of nitrogen into the carbon dots resulted in a remarkable 27.6-fold increase in fluorescence intensity, featuring a peak emission at 405 nm when excited at 330 nm and a significant fluorescence quantum yield of 22.5%. These N-L-Ser-CDs displayed a specific binding affinity for Cu

Indexed as

Amino AcidsCarbonCopperFluorescent DyesGlutathioneNitrogenQuantum DotsLimit of DetectionPyrolysisSolid-Phase Synthesis TechniquesSpectrometry, FluorescenceAmino AcidsCarbonCopperFluorescent DyesGlutathioneNitrogenAmino acid-based Carbon dotsCopper ionsGlutathione“on-off-on” Fluorescent ProbesSolid-phase Pyrolysis

Identifiers

PMID39985613

DOI10.1016/j.foodchem.2021.131142

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.