Evidence map›Paper›PMID 39985583›Full record

Trial reportEuropean journal of nutrition2025

A single dose of cajuína does not improve leukocyte count, lipid peroxidation, and physical performance in runners: a randomized, crossover, double‑blind, placebo study.

Luiz José Frota Solon-Júnior, Leonardo de Sousa Fortes, José Klinger da Silva Oliveira, Lydiane de Lima Tavares Toscano, Luiz Vieira da Silva Neto

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luiz José Frota Solon-JúniorDepartment of Biotechnology, Federal University of Ceará, Sobral, Ceará, Brazil. sluis424@gmail.com.ORCID http://orcid.org/0000-0002-5058-2542
Leonardo de Sousa FortesDepartment of Physical Education, Federal University of Paraíba, Campus I Lot. Cidade Universitaria, Joao Pessoa, PB, 58051-900, Brazil.ORCID http://orcid.org/0000-0002-0778-769X
José Klinger da Silva OliveiraState University Vale of Acaraú, Health Sciences Center, Sobral, Ceará, Brazil.ORCID http://orcid.org/0000-0003-1815-4625
Lydiane de Lima Tavares ToscanoDepartamento de Educação Física, Uninassau João Pessoa, João Pessoa, Brasil.ORCID http://orcid.org/0000-0003-0020-6220
Luiz Vieira da Silva NetoState University Vale of Acaraú, Health Sciences Center, Sobral, Ceará, Brazil.ORCID http://orcid.org/0000-0002-1890-3107

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the effects of a single dose of cajuína juice physical performance, leukocyte counts, and oxidative stress markers following a 10-km time trial in male runners.

methodsA total of nine recreationally trained male runners (32 ± 9.2 years; 70.9 ± 8.1 kg, 1.71 ± 0.06 m, 3.9 ± 1.9 training sessions per week) were randomly assigned to receive either cajuína juice (containing approximately one gram of vitamin C) or a placebo (a similar drink containing 0 mg of vitamin C) two hours before exercise, with a one-week washout period between interventions. Blood samples were collected immediately before ingestion and post-exercise. Leukocyte counts, as well as malondialdehyde (MDA), uric acid, and albumin concentrations, were analyzed from the samples.

resultsPhysical performance was not affected by cajuína intake (p > 0.05). Although a time effect (p = 0.01) was observed for MDA concentrations, no condition (p = 0.47) or interaction effects (p = 0.84) were revealed. Additionally, there were no effects of condition, time, and interaction for albumin (p = 0.83, p = 0.37, and p = 0.16, respectively) and uric acid (p = 0.64, p = 0.19, and p = 0.55, respectively) concentrations. No significant or positive changes in leukocyte counts were observed (p > 0.05).

conclusionThe single-dose intake of cajuína (Anacardium occidentale L.) does not improve leukocyte count, lipid peroxidation, or physical performance in recreationally trained male runners subjected to a 10-km time trial.

trial registrationThe study was registered in the Brazilian Clinical Trials Registry (REBEC) under the following registration number: RBR-3cb6qtz. The study was prospectively registered on November 17, 2023.

Indexed as

Athletic PerformanceFruit and Vegetable JuicesLipid PeroxidationPhysical Functional PerformanceRunningAdultAscorbic AcidCross-Over StudiesDouble-Blind MethodHumansLeukocyte CountMaleMalondialdehydeOxidative StressUric AcidYoung AdultAscorbic AcidMalondialdehydeUric AcidAnacardium occidentaleEnduranceErgogenic foodsImmunologyOxidative stress

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.