ArticleThe international journal of behavioral nutrition and physical activity2025
Is meeting 24-hour movement guidelines associated with a lower risk of frailty among adults?
Article in The international journal of behavioral nutrition and physical activity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Higher cystatin C, but not creatinine, predicts frailty risk in individuals with normal kidney function.The Journal of frailty & aging · 2026Article
- Effects of Isotemporal Substitution Analysis of Sedentary Behavior, Sleep, and Physical Activity on Physical Performance in Older Adults.Journal of prevention (2022) · 2026Article
- Does adherence to Canadian 24-Hour Movement Guidelines reduce all-cause mortality in patients with chronic kidney disease?Medicine · 2026Article
- The joint association of sleep duration and physical activity with frailty among older adults: the first evidence from CHARLS.BMC geriatrics · 2026Article
- Review
- Adherence to 24-hour movement guidelines and mortality risks in US cancer survivors: a national cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Joint Associations of Accelerometer-Derived Intensity Gradient and Diet Quality with Frailty Among Rural Chinese Older Adults.Nutrients · 2026Article
- Article
- Relationship between 24-h movement behaviors and frailty-a scoping review.Frontiers in public health · 2026Article
- Metabolic score for visceral fat as a superior predictor of frailty in overweight and obese adults: a cross-sectional NHANES analysis (2007-2020).Diabetology & metabolic syndrome · 2025Article
- Association between the geriatric nutritional risk index with the risk of frailty and mortality in the elderly population.Scientific reports · 2025Article
- Chain-mediated pathways of adults socioeconomic status affecting physical fitness in Macao: the role of motor skills and moderate to vigorous physical activity.Frontiers in public health · 2025Article
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5 authors.
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Abstract
backgroundThe relationship between 24-hour (24-h) movement guidelines and frailty remains unclear. We aimed to investigate the associations between meeting 24-h movement guidelines and frailty and to conduct secondary analyses by age, gender, and ethnicity.
methodsIn this study, we extracted data from the National Health and Nutrition Examination Survey (2007-2018) database. A total of 5,726 participants (50.25 ± 0.31 years) were included in this analysis, representing 38,240,356 noninstitutionalized U.S. INDIVIDUALS: Three 24-h movement behaviors, namely, physical activity, sedentary behavior (SB), and sleep, were self-reported using the standardized questionnaires. The 49-item frailty index was used to measure frailty. Multivariable logistic regression models and trend tests were used to examine the associations between meeting 24-h movement guidelines and frailty. Sensitivity analyses were also conducted to ensure the robustness of our results.
resultsThe total age-adjusted prevalence of frailty was 30.5%. In the fully adjusted model, compared with not meeting any of the 24-h movement guidelines, the adjusted odds ratios (AORs) of frailty were 0.786 (95% CI: 0.545, 1.133), 1.161 (95% CI: 0.787, 1.711), and 0.915 (95% CI: 0.616, 1.358) for participants meeting only moderate to vigorous physical activity (MVPA), only SB, and only sleep guidelines, respectively, but no statistically significant differences were observed (all P values > 0.05). Participants who met the SB + sleep guidelines (AOR = 0.613, 95% CI: 0.423, 0.887), MVPA + sleep guidelines (AOR = 0.389, 95% CI: 0.255, 0.593), and MVPA + SB guidelines (AOR = 0.555, 95% CI: 0.383, 0.806) presented a significantly lower risk of frailty by 39%, 61%, and 45%, respectively. Meeting all 3 guidelines (AOR = 0.377, 95% CI: 0.264, 0.539) and meeting 2 guidelines (AOR = 0.527, 95% CI: 0.377, 0.736) were associated with a lower risk of frailty (P value < 0.001), showing a linear trend (P for trend < 0.001). The strength of these associations varied somewhat by age, gender, and ethnicity.
conclusionsSignificant associations between the 24-h movement guidelines and frailty were observed among U.S. adults. Future studies are warranted to examine the causality and trajectory of these associations.
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