ReviewItalian journal of pediatrics2025
A blue blood toddler- a case report of methemoglobinemia and literature review.
Review in Italian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Severe methemoglobinemia resulting from intentional sodium hypochlorite poisoning in a 13-year-old girl hospitalized in the intensive care unit: a case report.Anaesthesiology intensive therapy · 2026Article
- Case Report: Methemoglobinemia associated with compound aminopyrine-phenacetin tablets supported by toxicological evidence.Frontiers in pharmacology · 2026Article
- Pediatric Methemoglobinemia Following Accidental Ingestion of Sodium Nitrite Used as a Sausage Preservative: A Case Report.Clinical case reports · 2025Article
- Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMethemoglobinemia (MetHb) is a rare and potentially life-threatening condition caused by oxidation of ferrous hemoglobin (Fe2+) to the ferric (Fe3+) state, making it incapable of binding oxygen and resulting in cyanosis and tissue ischemia. CASE PRESENTATION: This case presentation describes a 1-year-old boy who developed sudden cyanosis and reduced consciousness disorder. An initial assessment showed decreased oxygen saturation (SpO2 85%) despite oxygen therapy, while point-of-care venous blood gas (VBG) analysis assessed high rates of MetHb (72.7%). Methylene blue and ascorbic acid were administered, resulting in in rapid clinical recovery and normalized VBG test results. The trigger for this condition was not identified, however the most likely cause of poisoning was attributed to food oxidants.
conclusionStarting from the description of a clinical case, this paper discusses the causes and mechanisms of possible poisoning and reviews recent guidelines for methemoglobinemia management.
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