Evidence map›Paper›PMID 39984967›Full record

Observational studyJournal of translational medicine2025

Enhancing nutritional health and patient satisfaction five years after metabolic bariatric surgery with targeted supplementation.

Stefania Gorini, Elisabetta Camajani, Arianna Franchi, Edda Cava, Paolo Gentileschi, Alfonso Bellia, Sercan Karav, Paolo Sbraccia, Massimiliano Caprio, Mauro Lombardo

Registry-linked trialAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06664580 (Enhancing Nutritional Health and Patient Satisfaction Five Years After Metabolic Bariatric Surgery with Targeted Supplementation), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06664580 completednot on this map

Enhancing Nutritional Health and Patient Satisfaction Five Years After Metabolic Bariatric Surgery with Targeted Supplementation

TypeobservationalSponsorSan Raffaele Telematic UniversityRan2017 to 2024Enrolled249ConditionsObesity and Overweight, Nutritional Deficiency, Bariatric SurgeryArmsMetabolic Bariatric Surgery Procedures
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Stefania Gorini *Department for the Promotion of Human Science and Quality of Life, San Raffaele Open University, Rome, Italy.
Elisabetta Camajani *Department for the Promotion of Human Science and Quality of Life, San Raffaele Open University, Rome, Italy.
Arianna FranchiDepartment for the Promotion of Human Science and Quality of Life, San Raffaele Open University, Rome, Italy.
Edda CavaClinical Nutrition and Dietetics, San Camillo Forlanini Hospital, Rome, cir.ne Gianicolense 87, Rome, 00152, Italy.
Paolo GentileschiDepartment of Surgery, University of Rome Tor Vergata, Rome, Italy.
Alfonso BelliaDepartment of Systems Medicine, Tor Vergata University, Rome, Italy.
Sercan KaravDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Canakkale, 17000, Türkiye.
Paolo SbracciaDepartment of Systems Medicine, Tor Vergata University, Rome, Italy.
Massimiliano Caprio *Department for the Promotion of Human Science and Quality of Life, San Raffaele Open University, Rome, Italy.
Mauro Lombardo *Department for the Promotion of Human Science and Quality of Life, San Raffaele Open University, Rome, Italy. mauro.lombardo@uniroma5.it.ORCID 0000-0001-7509-5487

Funding

IRCCS San Raffaele Pisana PrinMIUR MIUR (Progetti di Ricerca di Interesse Nazionale 2022-Project code 202285HFZY -to MC, Work Package Leader)
6 · The paper itself

Abstract

backgroundThis study analyzes the long-term outcomes of metabolic bariatric surgery (MBS), focusing on weight loss, nutritional deficiencies, and patient satisfaction. We evaluate different surgical techniques to identify their impact on these outcomes.

methodsA five-year retrospective analysis was conducted on 249 patients who underwent MBS at a specialized center. Baseline characteristics included an average age of 38.5 years, weight of 118.5 kg, and BMI of 43.2 kg/m². Weight loss outcomes were assessed using mean excess weight loss (%EWL) at 60 months. Surgical techniques included laparoscopic sleeve gastrectomy (LSG), one anastomosis gastric bypass (OAGB), and Roux-en-Y gastric bypass (RYGB). Nutritional deficiencies and patient-reported quality of life were also evaluated.

resultsThe mean %EWL at 60 months was 92.1% ± 25.8% (p = 0.013). While LSG and OAGB showed similar weight loss patterns, RYGB resulted in further weight reduction from the third year onwards. Patients revised from LSG to RYGB had significantly greater weight loss (102.1%) compared to those revised to mini-gastric bypass (MGB) (84.6%, p < 0.05). Nutritional deficiencies were prevalent, with 41.2% of revised LSG patients experiencing iron deficiency and 14.3% developing new vitamin D deficiencies (p < 0.05). Most patients (85%) reported improvements in quality of life, and 85% expressed a willingness to undergo surgery again (p = 0.0028).

conclusionsMBS resulted in substantial and sustained weight loss, particularly in RYGB patients. Surgical revisions, especially from LSG to RYGB, were associated with greater weight loss but also increased nutritional risks. Persistent iron and vitamin D deficiencies highlight the necessity of individualized supplementation and long-term monitoring. Type-targeted supplementation represents an innovative approach to optimizing long-term nutritional support in bariatric patients. Future studies with larger cohorts and validated tools are needed to confirm these findings and strengthen clinical guidelines.

trial registrationThis study is registered at ClinicalTrials.gov (NCT06664580).

Indexed as

Bariatric SurgeryDietary SupplementsNutritional StatusPatient SatisfactionAdultFemaleHumansMaleMiddle AgedQuality of LifeTreatment OutcomeWeight LossBariatric supplementationLong-term weight maintenanceMetabolic bariatric surgeryNutritional healthPatient satisfactionPersonalized nutritionPostoperative outcomesRoux-en-Y gastric bypassSleeve gastrectomyTargeted supplementation

Identifiers

PMID39984967
PMCPMC11846221

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.