ArticleBMC cancer2025
Incidence trends of early-onset breast cancer by lifestyle risk factors.
Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Relationship Between Climate Change and Breast Cancer and Its Management and Preventative Implications in South Africa.International journal of environmental research and public health · 2025Pooled it
- Breast cancer diagnosis as a window of opportunity for smoking cessation: analysis of changes in smoking behaviour in 736 smoking breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Early- versus late-onset mortality trends in breast and female genital cancers in Spain, 1999-2024.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Article
- Influence of lifestyle factors on breast cancer incidence from mid-life to older age: an Australian longitudinal cohort study.BMJ open · 2026Article
- Female cancers in adolescent and young adult women: global inequities and 2050 burden estimates from GLOBOCAN 2022.Frontiers in oncology · 2026Article
- Article
- Understanding Breast Cancer: Awareness, Risk Factors, and Symptoms Among Female Health Science Students in Hungary.Healthcare (Basel, Switzerland) · 2025Article
- Microbiome-Induced Microenvironmental Changes Before and After Breast Cancer Treatment.Microorganisms · 2025Article
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16 authors.
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Abstract
backgroundThe incidence of early-onset breast cancer (< 50 years) has been increasing over the past decades with the role of modifiable, lifestyle-related risk factors remaining mostly unidentified.
methodsTo investigate the role of key lifestyle factors in the incidence trends of early-onset breast cancer (EOBC), we pooled data from six health studies in Finland in 1972-2015 and combined them with breast cancer data from the Finnish Cancer Registry. The cohort consisted of 56,253 women with 397 EOBCs. The effects of risk factors (hazard ratios) on EOBC and average annual percent change (AAPC) of incidence were estimated using Poisson regression models.
resultsThe highest annual increase in age-standardized incidence was observed among women aged 40-49 who were overweight (AAPC 4.0%, 95% CI 0.5-7.7%), currently smoking (AAPC 3.3%, 95% CI 0.1-6.6%) or moderately physically active (AAPC 2.9%, 95% CI 0.3-5.6%).
conclusionsThe increase in early-onset breast cancer incidence was highest among women aged 40-49 who were overweight, currently smoking, or moderately physically active, while no change by risk factors was found in women under 40 years of age. Our findings suggest a different type of cancer process in young adults and highlight the importance of lifestyle risk factors in the incidence of EOBC.
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