Evidence map›Paper›PMID 39984877›Full record

ArticleBMC gastroenterology2025

Immune-nutritional indicators predict short-term mortality in older patients after emergency gastrointestinal surgery: a retrospective study.

Zechuan Jin, Tinghan Yang, Ziqiang Wang

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zechuan JinColorectal Cancer Center, Department of General Surgery, West China Hospital, Sichuan University, Guo Xue Xiang No. 37, Chengdu, 610041, China.
Tinghan YangColorectal Cancer Center, Department of General Surgery, West China Hospital, Sichuan University, Guo Xue Xiang No. 37, Chengdu, 610041, China.
Ziqiang WangColorectal Cancer Center, Department of General Surgery, West China Hospital, Sichuan University, Guo Xue Xiang No. 37, Chengdu, 610041, China. wangziqiang@scu.edu.cn.

Funding

1·3·5 project for disciplines of excellence-Clinical Research Incubation Project, and West China Hospital, Sichuan University 22HXFH001Department of Science and Technology of Sichuan Province 2023NSFSC1834
6 · The paper itself

Abstract

backgroundThe aim of this study was to discover immune-nutritional indicators that can preoperatively predict short-term mortality in older patients undergoing emergency gastrointestinal surgery.

methodsWe retrospectively analyzed older patients older than 65 years of age who underwent various types of emergency gastrointestinal surgery under general anesthesia between January 2012 and December 2023. The immune-nutritional indicators were defined according to previous literature. The primary endpoint of this study was 90-day survival after surgery.

resultsA total of 4120 patients older than 65 years were included in this study. ROC curves and the decision curve analysis for eight factors predicting 90-day postoperative survival were well predicted by the mGPS (0.68, 95% CI: 0.66-0.70), PNI (0.68, 95% CI: 0.66-0.71) and CONUT score (0.68, 95% CI: 0.66-0.70). The models constructed by LASSO Cox and CoxBoost were used to score the risk for each patient, and the high LASSO Cox model risk score group had worse 90-day survival than the low score group, whereas patients in the low CoxBoost model score group had a worse prognosis. The AUC of the CoxBoost model was greater than that of the LASSO Cox model. A nomogram model was constructed using the variables screened by the LASSO Cox model with a C-index of 0.706.

conclusionsImmune-nutritional factors could be a favorable predictor for older patients undergoing emergency gastrointestinal surgery.

Indexed as

Digestive System Surgical ProceduresNutritional StatusAgedAged, 80 and overEmergenciesFemaleHumansMaleNomogramsPrognosisProportional Hazards ModelsRetrospective StudiesRisk AssessmentROC CurveEmergency gastrointestinal surgeryImmune-nutritional indicatorsOlder patientsShort-term mortality

Identifiers

PMID39984877
PMCPMC11844028

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.