Evidence map›Paper›PMID 39984854›Full record

ArticleBMC pregnancy and childbirth2025

The relationship between fear of childbirth and prenatal depression in pregnant women during pregnancy: a cross-lagged analysis.

Qian Jing, Jiang Jie, Xu Ke, Yang Liu, Deng Xiumin, Li Xiuchuan, Li Jinzhi

Abstract read
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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. [Prenatal fear stress impairs cognitive development in offspring rats by disrupting placental amino acid transport].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  4. Article
  5. Article
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Qian Jing *School of Nursing, Bengbu Medical College, An Hui Province, Beng Bu, People's Republic of China.
Jiang Jie *School of Nursing, Bengbu Medical College, An Hui Province, Beng Bu, People's Republic of China.
Xu KeSchool of Nursing, Bengbu Medical College, An Hui Province, Beng Bu, People's Republic of China.
Yang LiuSchool of Nursing, Bengbu Medical College, An Hui Province, Beng Bu, People's Republic of China.
Deng XiuminSchool of Nursing, Bengbu Medical College, An Hui Province, Beng Bu, People's Republic of China.
Li XiuchuanDepartment of Nursing, The First Affiliated Hospital of Bengbu Medical College, Bengbu, An Hui Province, China. Qjing0531@outlook.com.
Li JinzhiSchool of Nursing, Bengbu Medical College, An Hui Province, Beng Bu, People's Republic of China. qj20211011013@outlook.com.

Funding

Bengbu Medical College Graduate Research and Innovation Program Byycx22076Humanities and Social Sciences Key Research Project of Anhui Provincial Education Department 2022AH051414
6 · The paper itself

Abstract

objectiveTo analyze the reciprocal predictive relationship or quasi-causal relationship between fear of childbirth and antenatal depression in pregnant women via cross-lagged modeling.

methodsPregnant women who attended prenatal examinations at a Grade 3 A hospital in Bengbu City, Anhui Province, from November 2022 to March 2023 were randomly selected as the study subjects. A total of 219 pregnant women were followed up longitudinally three times during pregnancy using the General Information Questionnaire, the Wijma Expectation/Experience of Childbirth Questionnaire, and the Edinburgh Postnatal Depression Inventory, and were then statistically analyzed using a cross-lagged model.

resultsThe results revealed a positive correlation between maternal fear of childbirth and prenatal depression score on all three measures (r = 0.426, 0.519, 0.420, P < 0.001). Repeated measures ANOVA showed that maternal fear of childbirth tended to gradually increase during pregnancy, while prenatal depression first decreased and then stabilized. The results of the cross-lagged model showed that the T1 and T2 fear of childbirth scores significantly predicted the T2 and T3 prenatal depression scores (β = 0.184, 0.112, P < 0.05). The T1 fear of childbirth score significantly predicted the T2 fear of childbirth score (β = 0.127, P < 0.05), but the T2 fear of childbirth score was not significantly predictive of the T3 fear of childbirth score (β = 0.060, P > 0.05).

conclusionFear of childbirth and antenatal depression interact with each other during pregnancy, and this relationship develops dynamically, with fear of childbirth having a more stable and lasting predictive effect on antenatal depression. Maternal mental health status can be assessed early in pregnancy via our pregnancy health care services to guide targeted interventions throughout the perinatal period.

Indexed as

DepressionFearParturitionPregnancy ComplicationsPregnant PeopleAdultChinaFemaleHumansLongitudinal StudiesPregnancyPsychiatric Status Rating ScalesSurveys and QuestionnairesYoung AdultCross-lagged analysisFear of childbirthPregnant womenPrenatal depression

Identifiers

PMID39984854
PMCPMC11846457

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