Evidence map›Paper›PMID 39984719›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

Neonatal pulmonary function tests in infants born to COVID-19 positive mothers.

Katy Ruch, Kelvin D MacDonald, Kseniya Parkhotyuk, Diane Schilling, Mathew Olson, Shawn Mehess, Kristin Milner, Cindy T McEvoy

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katy RuchDivision of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0001-5507-2421
Kelvin D MacDonaldDivision of Pediatric Pulmonology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.ORCID http://orcid.org/0000-0002-6716-8559
Kseniya ParkhotyukDivision of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.
Diane SchillingDivision of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.
Mathew OlsonDivision of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.
Shawn MehessDepartment of Psychology, Portland State University, Portland, OR, USA.
Kristin MilnerDivision of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.
Cindy T McEvoyDivision of Neonatology, Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA. mcevoyc@ohsu.edu.ORCID http://orcid.org/0000-0001-8501-8813

Funding

Oregon Clinical and Translational Research InstituteUL1TR000128 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$28.7M
U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (NCATS) UL1TR000128
6 · The paper itself

Abstract

objectiveTo compare pulmonary function tests (PFTs), specifically passive respiratory system compliance (Crs), in infants of mothers positive for COVID-19 during pregnancy compared to PFTs from a historical cohort of matched, healthy reference infants. STUDY

designA prospective cohort study of infants born to COVID-19 positive mothers. Crs was measured with the single breath occlusion technique. Historical cohort data was obtained from a pre-COVID-19 data repository. Respiratory questionnaires were done at 1-year postnatal age.

resultsTwenty-four PFTs in the COVID-19 cohort were compared with PFTs from 24 reference subjects. Infants of the COVID-19 positive mothers had a Crs of 3.57 ml/cmH2O versus 3.76 mL/cmH2O in the reference group (p > 0.05). The remaining PFT outcomes were comparable between groups. The COVID-19 infants reported more allergic symptoms and conditions through 1-year.

conclusionWe found no difference in Crs in infants of mothers with COVID-19 during pregnancy compared to a historical pre-COVID reference cohort.

Indexed as

COVID-19Pregnancy Complications, InfectiousRespiratory Function TestsAdultCase-Control StudiesFemaleHumansInfantInfant, NewbornLung ComplianceMalePregnancyProspective StudiesSARS-CoV-2

Identifiers

PMID39984719

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.