Evidence map›Paper›PMID 39984629›Full record

ArticleScientific reports2025

Outcome of HIV patients on ART during the war and siege in a tertiary hospital in Northern Ethiopia: a cross-sectional study.

Migbnesh Gebremedhin Weledegebriel, Afewerki Tesfahunegn Nigusse, Tekae Gebru, Hansa Haftu, Teklu Gebrehiwet, Niguse Tsegay, Bisrat Tesfay Abera, Eden Kassahun, Atsede Gebrekidan, Berhane Yohannes Hailu and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Migbnesh Gebremedhin WeledegebrielDepartment of Internal Medicine, College of Health Sciences, Mekelle University, Mekelle, Tigray, Ethiopia. migbey12@gmail.com.
Afewerki Tesfahunegn NigusseDepartment of Epidemiology, College of Health Science, Mekelle University, Mekelle, Tigray, Ethiopia.
Tekae GebruDepartment of Pediatrics and Child Health, College of Health Science, Mekelle University, Mekelle, Tigray, Ethiopia.
Hansa HaftuDepartment of Pediatrics and Child Health, College of Health Science, Mekelle University, Mekelle, Tigray, Ethiopia.
Teklu GebrehiwetDepartment of Clinical Pharmacy, College of Health Science, Mekelle University, Mekelle, Tigray, Ethiopia.
Niguse TsegayDepartment of Pediatrics and Child Health, College of Health Science, Mekelle University, Mekelle, Tigray, Ethiopia.
Bisrat Tesfay AberaDepartment of Internal Medicine, College of Health Sciences, Mekelle University, Mekelle, Tigray, Ethiopia.
Eden KassahunAyder Comprehensive Specialized Hospital, Mekelle University, Mekelle, Tigray, Ethiopia.
Atsede GebrekidanDepartment of Pediatrics and Child Health, College of Health Science, Mekelle University, Mekelle, Tigray, Ethiopia.
Berhane Yohannes HailuDepartment of Clinical Pharmacy, College of Health Science, Mekelle University, Mekelle, Tigray, Ethiopia.
Samuel KidaneHealth Professionals Network for Tigray, Mekelle, Ethiopia.
Rishan Tesfay DestaHealth Professionals Network for Tigray, Mekelle, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The war and siege in Tigray, Ethiopia, have devastated the region's health system, critically impacting care for people living with HIV. This study aimed to assess the outcomes and factors affecting HIV patients during this crisis. An independent, repeated cross-sectional study was conducted at Ayder Comprehensive Specialized Hospital between October and November 2022. Data from prewar and during the war periods were analyzed using descriptive statistics and logistic regression. Among 440 participants (mean ages: 39 prewar and 41.2 during war), poor outcomes increased significantly during the war (28.6% prewar vs. 54.5% during war, p < 0.001). ART drug availability dropped by 68.8%, while only 10.6% and 30.7% accessed IPT and CPT, respectively. Services like CD4 and viral load determinations were severely disrupted (p < 0.001), with frequent ART switches and more missed appointments. Prewar factors associated with poor outcomes included severe malnutrition (AOR 3.98; 95% CI 1.04-15.22) and viral load > 1000 copies (AOR 6.68; 95% CI 2.91-15.32). During the crisis, significant factors included travel from distant areas (AOR 2.56; 95% CI 1.14-5.74), CD4 count > 200 cells/ml (AOR 0.27; 95% CI 0.08-0.97). The war and siege in Tigray significantly worsened HIV outcomes by disrupting care services and limiting access to essential treatments.

Indexed as

Anti-HIV AgentsHIV InfectionsWarfareAdultCD4 Lymphocyte CountCross-Sectional StudiesEthiopiaFemaleHumansMaleMiddle AgedTertiary Care CentersTreatment OutcomeViral LoadYoung AdultAnti-HIV AgentsARTHIV/AIDSOutcomeWar

Identifiers

PMID39984629
PMCPMC11845719

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.