Evidence map›Paper›PMID 39984557›Full record

ArticleScientific reports2025

Extraction of mango seed kernels via super fluid extraction and their anti-H. pylori, anti-ovarian and anti prostate cancer properties.

Samy Selim, Mohammed S Almuhayawi, Mohammed H Alruhaili, Mohanned T Alharbi, Faisal A Alraddadi, Moayad S Waznah, Duaa A Bukhari, Noura N Alzahofi, Wael A Obaid, Amna A Saddiq and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Samy SelimDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia. sabdulsalam@ju.edu.sa.
Mohammed S AlmuhayawiDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Mohammed H AlruhailiDepartment of Clinical Microbiology and Immunology, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Mohanned T AlharbiDepartment of Basic Medical Sciences, College of Medicine, University of Jeddah, Jeddah, Saudi Arabia.
Faisal A AlraddadiDepartment of Biology, College of Science, Taibah University, Madinah, 42353, Saudi Arabia.
Moayad S WaznahDepartment of Biology, College of Science, Taibah University, Madinah, 42353, Saudi Arabia.
Duaa A BukhariDepartment of Biology, College of Science, Taibah University, Madinah, 42353, Saudi Arabia.
Noura N AlzahofiDepartment of Biology, College of Science, Taibah University, Madinah, 42353, Saudi Arabia.
Wael A ObaidDepartment of Biology, College of Science, Taibah University, Madinah, 42353, Saudi Arabia.
Amna A SaddiqDepartment of Biological Sciences, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia.
Afra M BaghdadiDepartment of Biological Sciences, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia.
Ashwag Jaman AlzahraniDepartment of Biological Sciences, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia.
Mohammed A AlfattahDepartment of Biology, College of Science, Jazan University, P.O. Box. 114, Jazan, 45142, Kingdom of Saudi Arabia.
Soad K Al JaouniDepartment of Hematology/Oncology, Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the discovery of many plant-based drugs, research is still ingoing, in addition to using safer and more effective methods in the extraction process. Presently, Super Fluid Extraction (SFE) was applied to extract the mango seed kernels (MSK) at two operating temperatures 30 and 50 °C with studying their biological activities. MSK extract via SFE at operating temperatures 30 °C showed high yield 0.268 g compared to that at 50 °C. High-performance liquid chromatography (HPLC) analysis demonstrated high content of compounds such as gallic acid (68503.01 µg/mL), chlorogenic acid (6541.68 µg/mL), ferulic acid (2555.12 µg/mL) and ellagic acid (2479.42 µg/mL) MSK while at 50 °C the concentrations were low. Helicobacter pylori was highly inhibited by MSK extract via SFE at operating temperature 30 °C with inhibition zone 29.17 ± 0.29 mm, MIC 15.62 µg/mL and MBC 31.25 µg/mL, while at operating temperature 50 °C the inhibition zone was 24.67 ± 0.58 mm, MIC was 62.5 µg/mL and MBC was 125 µg/mL. Moreover, low hemolysis was recorded by H. pylori treated by MSK extract via SFE at operating temperature 30 °C compared to that at 50 °C. Excellent antioxidant with IC

Indexed as

Anti-Bacterial AgentsAntineoplastic Agents, PhytogenicHelicobacter pyloriMangiferaOvarian NeoplasmsPlant ExtractsProstatic NeoplasmsSeedsAntioxidantsCell Line, TumorChromatography, High Pressure LiquidChromatography, Supercritical FluidFemaleHumansMaleMicrobial Sensitivity TestsAnti-Bacterial AgentsAntineoplastic Agents, PhytogenicAntioxidantsPlant ExtractsCancerExtractionHelicobacter pyloriMangifera indicaSeed kernels

Identifiers

PMID39984557
PMCPMC11845699

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.