ArticleScientific reports2025
Unexpectedly high rate of unrecognized acute kidney injury and its trend over the past 14 years.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Association Between Preoperative Frailty and Postoperative Acute Kidney Injury, Complications, and Resource Utilization in Older Patients Undergoing Hip Fracture Surgery.Geriatrics & gerontology international · 2026Article
- Impact of Chronic Kidney Disease Severity on COVID-19 Outcomes: A Retrospective Cohort Study.Healthcare (Basel, Switzerland) · 2026Article
- Validation of Recorded Diagnoses of Acute Kidney Injury Among Surgical Patients in the Japanese Diagnosis Procedure Combination Database.Journal of epidemiology · 2026Article
- Multi-Omic and Spatial Profiling Identifies an Epithelial DKK1 Associated with Microenvironmental Remodeling in Pancreatic Ductal Adenocarcinoma.Current issues in molecular biology · 2026Article
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Authors and funding
12 authors.
Funding
Abstract
Acute kidney injury (AKI) is a frequent yet often overlooked complication. This study examines the incidence, unrecognized rate, and outcomes of AKI in adults at a large public Chinese hospital from 2010 to 2023. AKI rates were calculated, and outcomes were assessed using follow-up records. Multivariate logistic regression identified risk factors for unrecognized AKI. Among 2,790,540 patients, 5,080 met the AKI criteria, with an overall incidence of 0.18% (0.78% in hospitalizations, 0.05% in outpatients). The unrecognized AKI was 76.3%. In this group, 75% were stage 1, 16.7% stage 2, and 8.3% stage 3. Orthopedics had the highest unrecognized rate (94.5%) and ICUs the lowest (55.77%). Unrecognition of AKI improved from 90.3% in 2010-2011 to 70.2% in 2022-2023. AKI stage progression was linked to poorer survival. Patients with recognized AKI recovered faster than those with unrecognized AKI (8.0 vs. 9.0 days, p < 0.001). The mean follow-up time was 15.8 days, with similar rates at 28 and 90 days post-AKI for both groups. Risk factors for unrecognized AKI included lower AKI stage, baseline creatinine, absence of shock/heart disease/hypertension, and non-nephrology/surgery admissions. Non-nephrology physicians' unfamiliarity with AKI guidelines may contribute to low awareness. Improved early detection and monitoring in high-risk groups are needed.
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