ArticleThe journal of nutrition, health & aging2025
Association between objective physical activity and frailty transition in community-dwelling prefrail Japanese older adults.
Article in The journal of nutrition, health & aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Associations of sociodemographic and behavioral factors with frailty transition patterns: a multi-state Markov analysis of the China Health and Retirement Longitudinal Study (CHARLS).Archives of public health = Archives belges de sante publique · 2026Article
- Article
- The mediating role of cognitive function in the association between physical activity and frailty risk.Scientific reports · 2026Article
- Relationship between 24-h movement behaviors and frailty-a scoping review.Frontiers in public health · 2026Article
- The Frailty, Fitness, and Psychophysical/Social Condition of Community-Dwelling Older Adults-Analysis of 5-Year Longitudinal Data.Geriatrics (Basel, Switzerland) · 2025Article
- Lifestyle interventions in older adults with type 2 diabetes mellitus: The key for healthy ageing.The journal of nutrition, health & aging · 2025Article
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8 authors.
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Abstract
backgroundFrailty transition is common, and increased physical activity can prevent it. An objective assessment of physical activity could eliminate bias and provide more precise information on the association between frailty transitions and physical activity.
objectivesThis study aimed to examine the association between objective physical activity and frailty transition in community-dwelling prefrail Japanese older adults.
designThis is a retrospective cohort study based on the National Institute for Longevity Science-Longitudinal Study of Aging data.
participantsA total of 387 community-dwelling older adults with prefrailty were enrolled (mean age 72.0 years). MEASUREMENTS: Frailty was assessed using modified components of the Cardiovascular Health Study criteria, and frailty statuses were reassessed two years later. The frailty transitions were categorized into three groups: deterioration, persistence, and reversal. Participants wore a uniaxial accelerometer to assess the physical activities. Differences in baseline characteristics according to frailty transitions were assessed. To compare the baseline objective physical activities based on frailty transition, a general linear model and a logistic regression model were used.
resultsAmong the 387 participants, 40 (10.3%) deteriorated to frailty, 97 (25.0%) reversed to robust, and the majority (n = 250, 64.6%) remained prefrail after a 2-year follow-up. Using the general linear model, after adjusting for other factors, total energy expenditure (TEE) in the reversal group was significantly higher than that in the deterioration and persistence groups. No differences in TEE were observed between the persistence and deterioration groups. No significant differences existed in the numbers of daily steps, exercise energy expenditure (EEE) and physical activity with different intensity among these three groups. The logistic model also showed a significant association between TEE and the reversal of frailty.
conclusionFrailty transitions were common in the Japanese prefrail population. This study showed that a higher TEE was positively associated with frailty reversal in prefrail older adults. Promoting proactive programs for older adults to increase physical activity could help them stay healthy and prevent frailty deterioration.
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