Evidence map›Paper›PMID 39983140›Full record

ArticlePhysical review letters2025

Direct and Retrograde Wave Propagation in Unidirectionally Coupled Wilson-Cowan Oscillators.

Guy Elisha, Richard Gast, Sourav Halder, Sara A Solla, Peter J Kahrilas, John E Pandolfino, Neelesh A Patankar

Abstract read
In one paragraph

Article in Physical review letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guy ElishaNorthwestern University, Department of Mechanical Engineering, Evanston, Illinois, USA.
Richard GastNorthwestern University, Department of Neuroscience, Feinberg School of Medicine, Evanston, Illinois, USA.
Sourav HalderNorthwestern University, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Evanston, Illinois, USA.
Sara A SollaNorthwestern University, Department of Neuroscience, Feinberg School of Medicine, Evanston, Illinois, USA.
Peter J KahrilasNorthwestern University, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Evanston, Illinois, USA.
John E PandolfinoNorthwestern University, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Evanston, Illinois, USA.
Neelesh A PatankarNorthwestern University, Department of Mechanical Engineering, Evanston, Illinois, USA.

Funding

Role of altered response to volumetric distension in esophageal diseaseP01DK117824 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2018 to 2022
$7.3M
The mechanics of symptom generation in dysphagiaR01DK079902 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2009 to 2017
$2.9M
Evolution of the Chicago Classification: Bridging Physiology and MechanicsR01DK137775 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Dustin Allan Carlson, JOHN E PANDOLFINO · 2024 to 2026
$1.3M
NIDDK NIH HHS P01 DK117824NIDDK NIH HHS R01 DK079902NIDDK NIH HHS R01 DK137775
6 · The paper itself

Abstract

Some biological systems exhibit both direct and retrograde propagating signal waves despite unidirectional coupling. To explain this phenomenon, we study a chain of unidirectionally coupled Wilson-Cowan oscillators. Surprisingly, we find that changes in the homogeneous global input to the chain suffice to reverse the wave propagation direction. To obtain insights, we analyze the frequencies and bifurcations of the limit cycle solutions of the chain as a function of the global input. Specifically, we determine that the directionality of wave propagation is controlled by differences in the intrinsic frequencies of oscillators caused by the differential proximity of the oscillators to a homoclinic bifurcation.

Identifiers

PMID39983140
PMCPMC12306084

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.