Evidence map›Paper›PMID 39983002›Full record

ArticleScience advances2025

Mitochondrial translation regulates terminal erythroid differentiation by maintaining iron homeostasis.

Tatsuya Morishima, Md Fakruddin, Yohei Kanamori, Takeshi Masuda, Akiko Ogawa, Yuxin Wang, Vivien A C Schoonenberg, Falk Butter, Yuichiro Arima, Takaaki Akaike and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tatsuya MorishimaLaboratory of Stem Cell Stress, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.ORCID 0000-0003-3876-3217
Md FakruddinLaboratory of Stem Cell Stress, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.ORCID 0000-0003-2720-9173
Yohei KanamoriDepartment of Molecular and Medical Pharmacology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Takeshi MasudaDepartment of Pharmaceutical Microbiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0003-0121-4783
Akiko OgawaDepartment of Modomics Biology and Medicine, IDAC, Tohoku University, Sendai, Japan.
Yuxin WangLaboratory of Stem Cell Stress, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
Vivien A C SchoonenbergQuantitative Proteomics, Institute of Molecular Biology, 55128 Mainz, Germany.ORCID 0000-0002-7865-7120
Falk ButterQuantitative Proteomics, Institute of Molecular Biology, 55128 Mainz, Germany.
Yuichiro ArimaLaboratory of Developmental Cardiology, IRCMS, Kumamoto University, Kumamoto, Japan.ORCID 0000-0002-9840-3347
Takaaki AkaikeDepartment of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, Japan.ORCID 0000-0002-0623-1710
Toshiro MoroishiDepartment of Molecular and Medical Pharmacology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0001-6419-3882
Kazuhito TomizawaDepartment of Molecular Physiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.ORCID 0000-0002-5663-2627
Toshio SudaLaboratory of Stem Cell Regulation, IRCMS, Kumamoto University, Kumamoto, Japan.ORCID 0000-0001-7540-1771
Fan-Yan WeiDepartment of Modomics Biology and Medicine, IDAC, Tohoku University, Sendai, Japan.ORCID 0000-0002-4843-724X
Hitoshi TakizawaLaboratory of Stem Cell Stress, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.ORCID 0000-0002-5276-5430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial tRNA taurine modifications mediated by mitochondrial tRNA translation optimization 1 (

Indexed as

Cell DifferentiationErythroid CellsErythropoiesisHomeostasisIronMitochondriaProtein BiosynthesisAnimalsErythroblastsHumansMiceMice, KnockoutMitochondrial ProteinsRNA, TransferUnfolded Protein ResponseIronMitochondrial ProteinsRNA, Transfer

Identifiers

PMID39983002
PMCPMC11844735

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.