Evidence map›Paper›PMID 39982743›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

A hormone-to-neuropeptide pathway inhibits sexual receptivity in immature

Jie Chen, Peiwen Zhu, Sihui Jin, Zhaokun Zhang, Simei Jiang, Sheng Li, Suning Liu, Qionglin Peng, Yufeng Pan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jie ChenThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing 210096, China.ORCID 0009-0005-1120-8805
Peiwen ZhuThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing 210096, China.
Sihui JinThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing 210096, China.
Zhaokun ZhangThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing 210096, China.
Simei JiangThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing 210096, China.ORCID 0009-0009-1949-0648
Sheng LiGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China.ORCID 0000-0002-4217-2367
Suning LiuGuangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology, Institute of Insect Science and Technology and School of Life Sciences, South China Normal University, Guangzhou 510631, China.ORCID 0000-0002-7738-6218
Qionglin PengThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing 210096, China.ORCID 0000-0002-2287-1363
Yufeng PanThe Key Laboratory of Developmental Genes and Human Disease, Jiangsu Key Laboratory of Brain Science and Medicine, School of Life Science and Technology, Southeast University, Nanjing 210096, China.ORCID 0000-0002-1535-9716

Funding

MOST | National Natural Science Foundation of China (NSFC) 32200829MOST | National Natural Science Foundation of China (NSFC) 32222013MOST | National Natural Science Foundation of China (NSFC) 32371067
6 · The paper itself

Abstract

Newborns, typically asexual, undergo a process of sexual transition to reach sexual maturity, but the regulatory mechanism underlying this transition is not clear. Here, we studied how female sexual behavior is modulated during sexual transition by hormones and neuromodulators in

Indexed as

Drosophila melanogasterDrosophila ProteinsNeuropeptidesSexual Behavior, AnimalSexual MaturationAnimalsEcdysoneFemaleNeuronsReceptors, SteroidSignal TransductionDrosophila ProteinsEcdysoneecdysone receptorLk protein, DrosophilaNeuropeptidesReceptors, Steroidecdysonefemale receptivityjuvenile hormoneneuropeptidesexual transition

Identifiers

PMID39982743
PMCPMC11874258

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.