SynthesisJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025
Correlation between diagnosis-to-ablation time and atrial fibrillation recurrence: a systematic review and meta-analysis.
Synthesis in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Diagnosis-to-Ablation Time and Atrial Arrhythmia Recurrence After Ablation.JAMA network open · 2026Observational
- Chronological age was not independently associated with ultra-early safety or arrhythmic outcomes after contemporary atrial fibrillation ablation: a real-world single-center study.Frontiers in medicine · 2026Article
- LAAEV-centric atrial failure phenotype and a novel integrative score for predicting early recurrence after AF ablation.Frontiers in cardiovascular medicine · 2026Article
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Authors and funding
6 authors.
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Abstract
backgroundThe time from the initial diagnosis of atrial fibrillation (AF) to the index ablation procedure, known as diagnosis-to-ablation time (DAT), is a modifiable risk factor that is correlated to affect the recurrence of AF. The objective of this meta-analysis was to examine the correlation between diagnosis-to-ablation time and AF recurrence.
methodsA systematic search was performed in PubMed, Google Scholar, and Cochrane Library from database inception till June 2024. Studies reporting diagnosis-to-ablation time and its relation with AF recurrence were included. The primary analysis evaluated outcomes segregated by DAT ≤ 1 year versus > 1 year. Random-effects model with the Mantel-Haenszel method was used to evaluate AF recurrence.
resultsOf the 9177 articles, only 6 observational studies got through the inclusion criteria with a total participant count of 14,862. DAT of greater than 1 year was associated with increased risk of AF recurrence in all the included studies while DAT of ≤ 1 year was correlated with lower risk of AF recurrence (RR, 0.76 (95% CI, 0.73-0.79); P < 0.01). Similarly, DAT of ≤ 3 years was correlated with lower AF recurrence risk (RR, 0.82 (95% CI, 0.79-0.85); P < 0.01).
conclusionEvidence from observational cohorts suggests that the optimum time for ablation in AF patients is less than 1 year and a DAT of ≤ 1 year is linked to 24% lower chances of recurrence in AF patients, compared to DAT of ≥ 1 year.
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