Evidence map›Paper›PMID 39982593›Full record

ArticleParasitology research2025

Kato-Katz versus urine POC-CCA for the diagnosis of Schistosoma mansoni in preschool-aged children in Homa Bay County, Kenya.

Phyllis Munyiva Isaiah, Bryan Nyawanda, Collins Okoyo, Peter Steinmann

Abstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasitology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Phyllis Munyiva IsaiahSwiss Tropical and Public Health Institute, Allschwil, Switzerland. phyllis.isaiah@swisstph.ch.
Bryan NyawandaSwiss Tropical and Public Health Institute, Allschwil, Switzerland.
Collins OkoyoEastern and Southern Africa Centre of International Parasite Control, Kenya Medical Research Institute, Nairobi, Kenya.
Peter SteinmannSwiss Tropical and Public Health Institute, Allschwil, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of schistosomiasis in preschool-aged children (PSAC) is challenging. The point-of-care circulating cathodic antigen (POC-CCA) assay offers potential improvements in diagnostic access in hard-to-reach areas over the conventional Kato-Katz (KK) test. This study compared the diagnostic accuracy of KK versus POC-CCA in stool and urine samples from PSAC in a PSAC population residing in a S. mansoni endemic hard-to-reach area in Kenya. Using combined positive results of both KK and POC-CCA tests as the "gold standard," the overall sensitivity of KK (57.6%; 95% CI, 49.1-65.8) was significantly lower than that of POC-CCA (73.2%; 95% CI, 65.0-80.4);

Indexed as

Antigens, HelminthPoint-of-Care SystemsSchistosoma mansoniSchistosomiasis mansoniAnimalsChild, PreschoolDiagnostic Tests, RoutineFecesFemaleHumansKenyaMaleSensitivity and SpecificityAntigens, HelminthKato-KatzPOC-CCAPreschool-aged childrenSchistosomiasis

Identifiers

PMID39982593
PMCPMC11845413

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.